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Home / Primary Antibodies

PIN1 Antibody (R31729)

SKU : BHA17105096

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NSJ Bioreagents

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Mfr.No.	R31729
Clonality	Polyclonal
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, also called DOD, is an enzyme that in humans is encoded by the PIN1 gene. It binds to a subset of proteins and thus plays a role as a post-phosphorylation control in regulating protein function. Studies have shown that the deregulation of PIN1 may play a pivotal role in various diseases. Notably, up-regulation of may be implicated in certain cancers, and the down-regulation may be implicated in Alzheimers disease. Inhibitors of PIN1 may have therapeutic implications for cancer and immune disorders. PIN1 activity regulates the outcome of proline-directed kinase (e.g. MAPK, CDK or GSK3) signalling and consequently regulates cell proliferation (in part through control of cyclin D1 levels and stability) and cell survival. It also has an essential role in maintaining cell proliferation and regulating cyclin D1 function.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	Human partial recombinant protein (AA 1-163) was used as the immunogen for this PIN1 antibody.
Isotype	IgG
Predicted Reactivity	Human, Mouse, Rat
Reactivity	Human, Mouse, Rat
Recombinant	No

Gene Id	5300

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	After reconstitution, the PIN1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	WB
Dilution	Western blot: 0.5-1ug/ml

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17105096	R31729	100 ug	$419		Add to Cart

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