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Home / Antibodies

Phospho-ZC3HC1 (S354) Antibody

BHA10540573
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Contact us to order
Tel
+1 866.986.9598
Email
[email protected]
Get a Quote
Ask Merchant
Request More Infos
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Uniprot Q86WB0
Database Links

HGNC:29913

KEGG:hsa:51530

STRING:9606.ENSP00000351052

UniGene:Hs.194157
Function Essential component of a SCF-type E3 ligase complex, SCF(NIPA), a complex that controls mitotic entry by mediating ubiquitination and subsequent degradation of cyclin B1 (CCNB1). Its cell-cycle-dependent phosphorylation regulates the assembly of the SCF(NIPA) complex, restricting CCNB1 ubiquitination activity to interphase. Its inactivation results in nuclear accumulation of CCNB1 in interphase and premature mitotic entry. May have an antiapoptotic role in NPM-ALK-mediated signaling events.
Tissue Specificity Widely expressed. Highly expressed in heart, skeletal muscle and testis. Expressed in brain, placenta, lung, kidney, liver, pancreas, spleen, thymus, prostate, ovary small intestine and colon. Weakly or not expressed in leukocytes.
Buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form Liquid
Format Liquid
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Storage Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications WB, IF, ELISA
Description WB ; IF ; ELISA, WB ; ELISA ; IF
Dilution

WB1:500-1:2000
IF1:200-1:1000
ELISA1:40000
Tested Application WB,IF,ELISA;WB:1/500-1/2000.IF:1/200-1/1000.ELISA:1/40000
Datasheet
Western Blotting(WB) Protocol
Immunofluorescence (IF) Protocol
ELISA Protocol
SKU Supplier No. Size Your price Quantity
BHA10540573 CSB-PA020296 100μg $168.78
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BHA10540573 CSB-PA020296 50μg $123
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