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Home / Antibodies

Phospho-SQSTM1/p62 (Ser366) Antibody

SKU : BHA12909263

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AFFINITY BIOSCIENCES LTD

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Mfr.No.	AF7374
Alternative Names	A170 ; DMRV ; EBI 3 associated protein of 60 kDa ; EBI 3 associated protein p60 ; EBI3 associated protein of 60 kDa ; EBI3 associated protein p60 ; EBI3-associated protein of 60 kDa ; EBIAP ; FTDALS3 ; MGC127197 ; ORCA ; OSF-6 ; Osi ; OSIL ; Oxidative stress induced like ; p60 ; p62 ; p62B ; Paget disease of bone 3 ; PDB 3 ; PDB3 ; Phosphotyrosine independent ligand for the Lck SH2 domain of 62 kDa ; Phosphotyrosine independent ligand for the Lck SH2 domain p62 ; Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa ; PKC-zeta-interacting protein ; Protein kinase C-zeta-interacting protein ; Sequestosome 1 ; Sequestosome-1 ; SQSTM 1 ; SQSTM_HUMAN ; Sqstm1 ; STAP ; STONE14 ; Ubiquitin binding protein p62 ; Ubiquitin-binding protein p62 ; ZIP 3 ; ZIP ; ZIP3 ;
Categories	Primary Antibodies ; Phospho Antibodies
Clonality	polyclonal
Immunogen	A synthesized peptide derived from human SQSTM1/p62 around the phosphorylation site of Ser366.
Molecular Weight	Observed Mol.Wt.: 62kDa. Predicted Mol.Wt.: 48kDa.
Reactivity	Human, Mouse, Rat
Specificity	Phospho-SQSTM1/p62 (Ser366) Antibody detects endogenous levels of SQSTM1/p62 only when phosphorylated at Ser366.
Subcellular Location	Cytoplasm. Late endosome. Nucleus. Sarcomere (By similarity). In cardiac muscles localizes to the sarcomeric band (By similarity). Localizes to late endosomes. May also localize to the nucleus. Accumulates in neurofibrillary tangles and in Lewy bodies of neurons from individuals with Alzheimer and Parkinson disease respectively. Enriched in Rosenthal fibers of pilocytic astrocytoma. In liver cells, accumulates in Mallory bodies associated with alcoholic hepatitis, Wilson disease, indian childhood cirrhosis and in hyaline bodies associated with hepatocellular carcinoma.

Uniprot

Q13501

Gene Id

8878

Sequence

10 20 30 40 50
MASLTVKAYL LGKEDAAREI RRFSFCCSPE PEAEAEAAAG PGPCERLLSR
60 70 80 90 100
VAALFPALRP GGFQAHYRDE DGDLVAFSSD EELTMAMSYV KDDIFRIYIK
110 120 130 140 150
EKKECRRDHR PPCAQEAPRN MVHPNVICDG CNGPVVGTRY KCSVCPDYDL
160 170 180 190 200
CSVCEGKGLH RGHTKLAFPS PFGHLSEGFS HSRWLRKVKH GHFGWPGWEM
210 220 230 240 250
GPPGNWSPRP PRAGEARPGP TAESASGPSE DPSVNFLKNV GESVAAALSP
260 270 280 290 300
LGIEVDIDVE HGGKRSRLTP VSPESSSTEE KSSSQPSSCC SDPSKPGGNV
310 320 330 340 350
EGATQSLAEQ MRKIALESEG RPEEQMESDN CSGGDDDWTH LSSKEVDPST
360 370 380 390 400
GELQSLQMPE SEGPSSLDPS QEGPTGLKEA ALYPHLPPEA DPRLIESLSQ
410 420 430 440
MLSMGFSDEG GWLTRLLQTK NYDIGAALDT IQYSKHPPPL

Concentration	1mg/ml
Format	Liquid
Purification	The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Storage Condition	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.

Applications	ELISA, IHC, WB
Dilution	WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Manual
MSDS
IHC Protocol.
Western Blotting Handbook.

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SKU	Supplier No.	Size	Your price	Quantity
BHA12909263	AF7374	100ul	$800		Add to Cart

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