Phospho-RUNX1 / AML1 (Ser249) Antibody

Mfr.No.	AF2316
Alternative Names	Acute myeloid leukemia 1 ; Acute myeloid leukemia 1 protein ; alpha subunit core binding factor ; AML 1 ; AML1 ; AML1 EVI 1 ; AML1 EVI 1 fusion protein ; Aml1 oncogene ; AMLCR 1 ; AMLCR1 ; CBF alpha 2 ; CBF-alpha-2 ; CBFA 2 ; CBFA2 ; Core binding factor alpha 2 subunit ; Core binding factor runt domain alpha subunit 2 ; Core-binding factor subunit alpha-2 ; EVI 1 ; EVI1 ; HGNC ; Oncogene AML 1 ; Oncogene AML-1 ; OTTHUMP00000108696 ; OTTHUMP00000108697 ; OTTHUMP00000108699 ; OTTHUMP00000108700 ; OTTHUMP00000108702 ; PEA2 alpha B ; PEA2-alpha B ; PEBP2 alpha B ; PEBP2-alpha B ; PEBP2A2 ; PEBP2aB ; Polyomavirus enhancer binding protein 2 alpha B subunit ; Polyomavirus enhancer-binding protein 2 alpha B subunit ; Run1 ; Runt related transcription factor 1 ; Runt-related transcription factor 1 ; RUNX 1 ; Runx1 ; RUNX1_HUMAN ; SL3 3 enhancer factor 1 alpha B subunit ; SL3-3 enhancer factor 1 alpha B subunit ; SL3/AKV core binding factor alpha B subunit ; SL3/AKV core-binding factor alpha B subunit ;
Categories	Primary Antibodies ; Phospho Antibodies
Clonality	polyclonal
Immunogen	A synthesized peptide derived from human AML1 around the phosphorylation site of Ser249.
Molecular Weight	Observed Mol.Wt.: 55kDa. Predicted Mol.Wt.: 49kDa.
Reactivity	Human, Rat
Specificity	Phospho-AML1 (Ser249) Antibody detects endogenous levels of AML1.
Subcellular Location	Nucleus.

Uniprot

Q01196

Gene Id

861

Sequence

10 20 30 40 50
MRIPVDASTS RRFTPPSTAL SPGKMSEALP LGAPDAGAAL AGKLRSGDRS
60 70 80 90 100
MVEVLADHPG ELVRTDSPNF LCSVLPTHWR CNKTLPIAFK VVALGDVPDG
110 120 130 140 150
TLVTVMAGND ENYSAELRNA TAAMKNQVAR FNDLRFVGRS GRGKSFTLTI
160 170 180 190 200
TVFTNPPQVA TYHRAIKITV DGPREPRRHR QKLDDQTKPG SLSFSERLSE
210 220 230 240 250
LEQLRRTAMR VSPHHPAPTP NPRASLNHST AFNPQPQSQM QDTRQIQPSP
260 270 280 290 300
PWSYDQSYQY LGSIASPSVH PATPISPGRA SGMTTLSAEL SSRLSTAPDL
310 320 330 340 350
TAFSDPRQFP ALPSISDPRM HYPGAFTYSP TPVTSGIGIG MSAMGSATRY
360 370 380 390 400
HTYLPPPYPG SSQAQGGPFQ ASSPSYHLYY GASAGSYQFS MVGGERSPPR
410 420 430 440 450
ILPPCTNAST GSALLNPSLP NQSDVVEAEG SHSNSPTNMA PSARLEEAVW

RPY

Concentration	1mg/ml
Format	Liquid
Purification	The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Storage Condition	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.