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Home / Primary Antibodies

Phospho-Retinoblastoma (Ser795) Antibody

SKU : BHA12902136

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AFFINITY BIOSCIENCES LTD

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Mfr.No.	AF3104
Alternative Names	Exon 17 tumor GOS561 substitution mutation causes premature stop ; GOS563 exon 17 substitution mutation causes premature stop ; OSRC ; Osteosarcoma ; p105-Rb ; P105RB ; PP105 ; pp110 ; PPP1R130 ; pRb ; Prepro retinoblastoma associated protein ; Protein phosphatase 1 regulatory subunit 130 ; Rb ; RB transcriptional corepressor 1 ; RB_HUMAN ; RB1 ; RB1 gene ; Retinoblastoma 1 ; Retinoblastoma suspectibility protein ; Retinoblastoma-associated protein ;
Categories	Primary Antibodies ; Phospho Antibodies
Clonality	polyclonal
Description	Retinoblastoma (RB) is an embryonic malignant neoplasm of retinal origin. It almost always presents in early childhood and is often bilateral. Spontaneous regression ('cure') occurs in some cases.
Immunogen	A synthesized peptide derived from human Retinoblastoma around the phosphorylation site of Serine 795.
Molecular Weight	Observed Mol.Wt.: 106kDa. Predicted Mol.Wt.: 107kDa.
Reactivity	Human, Mouse, Rat
Specificity	Phospho-Retinoblastoma (Ser795) Antibody detects endogenous levels of Retinoblastoma only when phosphorylated at Serine 795.
Subcellular Location	Nucleus.

Uniprot

P06400

Gene Id

5925

Sequence

10	20	30	40	50
MPPKTPRKTA	ATAAAAAAEP	PAPPPPPPPE	EDPEQDSGPE	DLPLVRLEFE
60	70	80	90	100
ETEEPDFTAL	CQKLKIPDHV	RERAWLTWEK	VSSVDGVLGG	YIQKKKELWG
110	120	130	140	150
ICIFIAAVDL	DEMSFTFTEL	QKNIEISVHK	FFNLLKEIDT	STKVDNAMSR
160	170	180	190	200
LLKKYDVLFA	LFSKLERTCE	LIYLTQPSSS	ISTEINSALV	LKVSWITFLL
210	220	230	240	250
AKGEVLQMED	DLVISFQLML	CVLDYFIKLS	PPMLLKEPYK	TAVIPINGSP
260	270	280	290	300
RTPRRGQNRS	ARIAKQLEND	TRIIEVLCKE	HECNIDEVKN	VYFKNFIPFM
310	320	330	340	350
NSLGLVTSNG	LPEVENLSKR	YEEIYLKNKD	LDARLFLDHD	KTLQTDSIDS
360	370	380	390	400
FETQRTPRKS	NLDEEVNVIP	PHTPVRTVMN	TIQQLMMILN	SASDQPSENL
410	420	430	440	450
ISYFNNCTVN	PKESILKRVK	DIGYIFKEKF	AKAVGQGCVE	IGSQRYKLGV
460	470	480	490	500
RLYYRVMESM	LKSEEERLSI	QNFSKLLNDN	IFHMSLLACA	LEVVMATYSR
510	520	530	540	550
STSQNLDSGT	DLSFPWILNV	LNLKAFDFYK	VIESFIKAEG	NLTREMIKHL
560	570	580	590	600
ERCEHRIMES	LAWLSDSPLF	DLIKQSKDRE	GPTDHLESAC	PLNLPLQNNH
610	620	630	640	650
TAADMYLSPV	RSPKKKGSTT	RVNSTANAET	QATSAFQTQK	PLKSTSLSLF
660	670	680	690	700
YKKVYRLAYL	RLNTLCERLL	SEHPELEHII	WTLFQHTLQN	EYELMRDRHL
710	720	730	740	750
DQIMMCSMYG	ICKVKNIDLK	FKIIVTAYKD	LPHAVQETFK	RVLIKEEEYD
760	770	780	790	800
SIIVFYNSVF	MQRLKTNILQ	YASTRPPTLS	PIPHIPRSPY	KFPSSPLRIP
810	820	830	840	850
GGNIYISPLK	SPYKISEGLP	TPTKMTPRSR	ILVSIGESFG	TSEKFQKINQ
860	870	880	890	900
MVCNSDRVLK	RSAEGSNPPK	PLKKLRFDIE	GSDEADGSKH	LPGESKFQQK
910	920
LAEMTSTRTR	MQKQKMNDSM	DTSNKEEK

Concentration	1mg/ml
Format	Liquid
Purification	The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Storage Condition	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.

Applications	IF/ICC, ELISA, IHC, WB
Dilution	WB 1:500-1:2000 IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Manual
MSDS
IHC Protocol.
Western Blotting Handbook.

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SKU	Supplier No.	Size	Your price	Quantity
BHA12902136	AF3104	100ul	$280		Add to Cart
BHA12902136	AF3104	200ul	$350		Add to Cart

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