Phospho-PAK1 /PAK2 (Ser199/Ser204, Ser192/Ser197) Antibody

Mfr.No.	AF2380
Alternative Names	ADRB2 ; Alpha PAK ; Alpha-PAK ; MGC130000 ; MGC130001 ; p21 activated kinase 1 ; p21 protein (Cdc42/Rac) activated kinase 1 ; p21-activated kinase 1 ; p21/Cdc42/Rac1 activated kinase 1 (yeast Ste20 related) ; p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast) ; p65 PAK ; p65-PAK ; P68-PAK ; PAK alpha ; PAK-1 ; Pak1 ; PAK1_HUMAN ; Paka ; PAKalpha ; Protein kinase MUK2 ; Rac/p21-activated kinase ; Serine/threonine-protein kinase PAK 1 ; STE20 homolog yeast ; C-t-PAK2 ; CB422 ; EC 2.7.11.1 ; Gamma PAK ; Gamma-PAK ; hPAK65 ; Kinase ; p21 (CDKN1A) activated kinase 2 ; p21 (CDKN1A)-activated kinase 2a ; p21 activated kinase 2 ; p21 protein (Cdc42/Rac)-activated kinase 2 ; p21 protein Cdc42 Rac activated kinase 2 ; p21-activated kinase 2 ; p21-activated kinase, 65-KD ; p21-activated protein kinase I ; p21CDKN1A activated kinase 2 ; p27 ; p34 ; p58 ; p65PAK ; PAK 2 ; PAK-2 ; PAK-2p34 ; Pak2 ; PAK2_HUMAN ; PAK65 ; PAKgamma ; S6 H4 kinase ; S6/H4 kinase ; Serine threonine protein kinase PAK 2 ; Serine/threonine protein kinase PAK 2 ;
Categories	Primary Antibodies ; Phospho Antibodies
Clonality	polyclonal
Immunogen	A synthesized peptide derived from human PAK1 around the phosphorylation site of Ser199/204.
Molecular Weight	Observed Mol.Wt.: 61 to 67 (PAK2), 68 to 74 (PAK1/3)kDa. Predicted Mol.Wt.: 61kDa.
Reactivity	Human, Mouse, Rat
Specificity	Phospho-PAK1 (Ser199/204)/PAK2 (Ser192/197) Antibody detects endogenous levels of PAK1.
Subcellular Location	Cytoplasm. Cell junction > focal adhesion. Recruited to focal adhesions upon activation.

Uniprot

Q13153 ; Q13177

Gene Id

50585062

Sequence

10 20 30 40 50
MSNNGLDIQD KPPAPPMRNT STMIGAGSKD AGTLNHGSKP LPPNPEEKKK
60 70 80 90 100
KDRFYRSILP GDKTNKKKEK ERPEISLPSD FEHTIHVGFD AVTGEFTGMP
110 120 130 140 150
EQWARLLQTS NITKSEQKKN PQAVLDVLEF YNSKKTSNSQ KYMSFTDKSA
160 170 180 190 200
EDYNSSNALN VKAVSETPAV PPVSEDEDDD DDDATPPPVI APRPEHTKSV
210 220 230 240 250
YTRSVIEPLP VTPTRDVATS PISPTENNTT PPDALTRNTE KQKKKPKMSD
260 270 280 290 300
EEILEKLRSI VSVGDPKKKY TRFEKIGQGA SGTVYTAMDV ATGQEVAIKQ
310 320 330 340 350
MNLQQQPKKE LIINEILVMR ENKNPNIVNY LDSYLVGDEL WVVMEYLAGG
360 370 380 390 400
SLTDVVTETC MDEGQIAAVC RECLQALEFL HSNQVIHRDI KSDNILLGMD
410 420 430 440 450
GSVKLTDFGF CAQITPEQSK RSTMVGTPYW MAPEVVTRKA YGPKVDIWSL
460 470 480 490 500
GIMAIEMIEG EPPYLNENPL RALYLIATNG TPELQNPEKL SAIFRDFLNR
510 520 530 540
CLEMDVEKRG SAKELLQHQF LKIAKPLSSL TPLIAAAKEA TKNNH

Concentration	1mg/ml
Format	Liquid
Purification	The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Storage Condition	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.