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Home / Antibodies

Phospho-p21 Cip1 (Thr145) Antibody

SKU : BHA12902416

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AFFINITY BIOSCIENCES LTD

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Mfr.No.	AF3290
Alternative Names	CAP20 ; CDK-interacting protein 1 ; CDKI ; CDKN1 ; Cdkn1a ; CDN1A_HUMAN ; CIP1 ; Cyclin Dependent Kinase Inhibitor 1A ; Cyclin-dependent kinase inhibitor 1 ; Cyclin-dependent kinase inhibitor 1A (P21) ; Cyclin-dependent kinase inhibitor 1A (p21, Cip1) ; DNA Synthesis Inhibitor ; MDA-6 ; MDA6 ; Melanoma differentiation-associated protein 6 ; Melanoma differentiation-associated protein ; p21 ; P21 protein ; p21CIP1 ; p21Cip1/Waf1 ; p21WAF ; PIC1 ; SDI1 ; SLC12A9 ; WAF1 ; Wild type p53 activated fragment 1 (WAF1) ; Wild type p53 activated fragment 1 ; Wildtype p53-activated fragment 1 ;
Antigen	Phospho-p21 Cip1 (Thr145)
Categories	Primary Antibodies ; Phospho Antibodies
Clonality	polyclonal
Description	This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-CDK2 or -CDK4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli.
Immunogen	A synthesized peptide derived from human p21 Cip1 around the phosphorylation site of Threonine 145.
Molecular Weight	Observed Mol.Wt.: kDa. Predicted Mol.Wt.: 19kDa.
Reactivity	Human, Mouse, Rat
Specificity	Phospho-p21 Cip1 (Thr145) Antibody detects endogenous levels of p21 Cip1 only when phosphorylated at Threonine 145.
Subcellular Location	Cytoplasm. Nucleus.

Uniprot

P38936

Gene Id

1026

Sequence

10	20	30	40	50
MSEPAGDVRQ	NPCGSKACRR	LFGPVDSEQL	SRDCDALMAG	CIQEARERWN
60	70	80	90	100
FDFVTETPLE	GDFAWERVRG	LGLPKLYLPT	GPRRGRDELG	GGRRPGTSPA
110	120	130	140	150
LLQGTAEEDH	VDLSLSCTLV	PRSGEQAEGS	PGGPGDSQGR	KRRQTSMTDF
160
YHSKRRLIFS	KRKP

Concentration	1mg/ml
Format	Liquid
Purification	The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Storage Condition	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.

Applications	IF/ICC, ELISA, IHC, WB
Dilution	WB 1:500-1:2000 IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Manual
MSDS
IHC Protocol.
Western Blotting Handbook.

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SKU	Supplier No.	Size	Your price	Quantity
BHA12902416	AF3290	100ul	$280		Add to Cart
BHA12902416	AF3290	200ul	$350		Add to Cart

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