JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
[email protected]

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Primary Antibodies

Phospho-Nucleophosmin (Thr237) Antibody

SKU : BHA12905870

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Request More Infos

AFFINITY BIOSCIENCES LTD

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	AF8498
Alternative Names	B23 ; MGC104254 ; NO38 ; NPM ; NPM_HUMAN ; NPM1 ; Nucleolar phosphoprotein B23 ; Nucleolar protein NO38 ; Nucleophosmin (nucleolar phosphoprotein B23 numatrin) ; Nucleophosmin ; nucleophosmin nucleoplasmin family member 1 ; Nucleophosmin/nucleoplasmin family member 1 ; Numatrin ; OTTHUMP00000161024 ; OTTHUMP00000161025 ; OTTHUMP00000223397 ; OTTHUMP00000223398 ;
Categories	Primary Antibodies ; Phospho Antibodies
Clonality	polyclonal
Immunogen	A synthesized peptide derived from human NPM (Phospho-Thr237).
Molecular Weight	Observed Mol.Wt.: 32/38kDa. Predicted Mol.Wt.: 33kDa.
Reactivity	Human, Mouse, Rat
Specificity	NPM (Phospho-Thr237) Antibody detects endogenous levels of NPM only when phosphorylated at Thr237.
Subcellular Location	Nucleus, nucleolus. Nucleus, nucleoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Generally nucleolar, but is translocated to the nucleoplasm in case of serum starvation or treatment with anticancer drugs. Has been found in the cytoplasm in patients with primary acute myelogenous leukemia (AML), but not with secondary AML. Can shuttle between cytoplasm and nucleus. Co- localizes with the methylated form of RPS10 in the granular component (GC) region of the nucleolus. Colocalized with nucleolin and APEX1 in nucleoli. Isoform 1 of NEK2 is required for its localization to the centrosome during mitosis.

Uniprot

P06748

Gene Id

4869

Sequence

10	20	30	40	50
MEDSMDMDMS	PLRPQNYLFG	CELKADKDYH	FKVDNDENEH	QLSLRTVSLG
60	70	80	90	100
AGAKDELHIV	EAEAMNYEGS	PIKVTLATLK	MSVQPTVSLG	GFEITPPVVL
110	120	130	140	150
RLKCGSGPVH	ISGQHLVAVE	EDAESEDEEE	EDVKLLSISG	KRSAPGGGSK
160	170	180	190	200
VPQKKVKLAA	DEDDDDDDEE	DDDEDDDDDD	FDDEEAEEKA	PVKKSIRDTP
210	220	230	240	250
AKNAQKSNQN	GKDSKPSSTP	RSKGQESFKK	QEKTPKTPKG	PSSVEDIKAK
260	270	280	290
MQASIEKGGS	LPKVEAKFIN	YVKNCFRMTD	QEAIQDLWQW	RKSL

Concentration	1mg/ml
Format	Liquid
Purification	The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Storage Condition	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.

Applications	IF/ICC, ELISA, WB
Dilution	WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Manual
MSDS
IF/ICC Protocol.
Western Blotting Handbook.

No Description Available.

No Description Available.

Have you used this product?

Rate it now..!!

Login to Review

SKU	Supplier No.	Size	Your price	Quantity
BHA12905870	AF8498	100ul	$350		Add to Cart
BHA12905870	AF8498	200ul	$450		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2024 Biohippo. All rights reserved.