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Home / Primary Antibodies

Phospho-NR3C1 (Ser211) Antibody

SKU : BHA12903076

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AFFINITY BIOSCIENCES LTD

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Mfr.No.	AF2004
Alternative Names	GCCR ; GCR ; GCR_HUMAN ; glucocorticoid nuclear receptor variant 1 ; Glucocorticoid receptor ; Glucocorticoid receptor beta isoform ; GR ; GRL ; nr3c1 ; Nuclear receptor subfamily 3 group C member 1 ;
Categories	Primary Antibodies ; Phospho Antibodies
Clonality	polyclonal
Description	The protein encoded by this gene is a receptor for glucocorticoids and can act as both a transcription factor and a regulator of other transcription factors. The encoded protein can bind DNA as a homodimer or as a heterodimer with another protein such as the retinoid X receptor. This protein can also be found in heteromeric cytoplasmic complexes along with heat shock factors and immunophilins.
Immunogen	A synthesized peptide derived from human GR around the phosphorylation site of Serine 211.
Molecular Weight	Observed Mol.Wt.: 95kDa. Predicted Mol.Wt.: 86kDa.
Reactivity	Human, Mouse, Rat
Specificity	Phospho-GR (Ser211) Antibody detects endogenous levels of GR only when phosphorylated at Serine 211.
Subcellular Location	Cytoplasm. Nucleus. Cytoplasmic in the absence of ligand; nuclear after ligand-binding.

Uniprot

P04150

Gene Id

2908

Sequence

10	20	30	40	50
MDSKESLTPG	REENPSSVLA	QERGDVMDFY	KTLRGGATVK	VSASSPSLAV
60	70	80	90	100
ASQSDSKQRR	LLVDFPKGSV	SNAQQPDLSK	AVSLSMGLYM	GETETKVMGN
110	120	130	140	150
DLGFPQQGQI	SLSSGETDLK	LLEESIANLN	RSTSVPENPK	SSASTAVSAA
160	170	180	190	200
PTEKEFPKTH	SDVSSEQQHL	KGQTGTNGGN	VKLYTTDQST	FDILQDLEFS
210	220	230	240	250
SGSPGKETNE	SPWRSDLLID	ENCLLSPLAG	EDDSFLLEGN	SNEDCKPLIL
260	270	280	290	300
PDTKPKIKDN	GDLVLSSPSN	VTLPQVKTEK	EDFIELCTPG	VIKQEKLGTV
310	320	330	340	350
YCQASFPGAN	IIGNKMSAIS	VHGVSTSGGQ	MYHYDMNTAS	LSQQQDQKPI
360	370	380	390	400
FNVIPPIPVG	SENWNRCQGS	GDDNLTSLGT	LNFPGRTVFS	NGYSSPSMRP
410	420	430	440	450
DVSSPPSSSS	TATTGPPPKL	CLVCSDEASG	CHYGVLTCGS	CKVFFKRAVE
460	470	480	490	500
GQHNYLCAGR	NDCIIDKIRR	KNCPACRYRK	CLQAGMNLEA	RKTKKKIKGI
510	520	530	540	550
QQATTGVSQE	TSENPGNKTI	VPATLPQLTP	TLVSLLEVIE	PEVLYAGYDS
560	570	580	590	600
SVPDSTWRIM	TTLNMLGGRQ	VIAAVKWAKA	IPGFRNLHLD	DQMTLLQYSW
610	620	630	640	650
MFLMAFALGW	RSYRQSSANL	LCFAPDLIIN	EQRMTLPCMY	DQCKHMLYVS
660	670	680	690	700
SELHRLQVSY	EEYLCMKTLL	LLSSVPKDGL	KSQELFDEIR	MTYIKELGKA
710	720	730	740	750
IVKREGNSSQ	NWQRFYQLTK	LLDSMHEVVE	NLLNYCFQTF	LDKTMSIEFP
760	770
EMLAEIITNQ	IPKYSNGNIK	KLLFHQK

Concentration	1mg/ml
Format	Liquid
Purification	The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Storage Condition	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.

Applications	IF/ICC, ELISA, IHC, WB
Dilution	WB 1:500-1:2000 IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Manual
MSDS
IHC Protocol.
Western Blotting Handbook.

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SKU	Supplier No.	Size	Your price	Quantity
BHA12903076	AF2004	100ul	$280		Add to Cart
BHA12903076	AF2004	200ul	$350		Add to Cart

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