JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.
Loding Loading ....
Home / Antibodies

Phospho-MST1R (S1394) Antibody

BHA10538945
Contact us to order
Tel
+1 866.986.9598
Email
[email protected]
Get a Quote
Request More Infos
Order Now

Credit card payments now incur a 3% fee.

Contact us to order
Tel
+1 866.986.9598
Email
[email protected]
Get a Quote
Ask Merchant
Request More Infos
Sample Request
Uniprot Q04912
Database Links

HGNC:7381

OMIM:255995

KEGG:hsa:4486

STRING:9606.ENSP00000296474

UniGene:Hs.517973
Function Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to MST1 ligand. Regulates many physiological processes including cell survival, migration and differentiation. Ligand binding at the cell surface induces autophosphorylation of RON on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1 or the adapter GAB1. Recruitment of these downstream effectors by RON leads to the activation of several signaling cascades including the RAS-ERK, PI3 kinase-AKT, or PLCgamma-PKC. RON signaling activates the wound healing response by promoting epithelial cell migration, proliferation as well as survival at the wound site. Plays also a role in the innate immune response by regulating the migration and phagocytic activity of macrophages. Alternatively, RON can also promote signals such as cell migration and proliferation in response to growth factors other than MST1 ligand.
Protein Families Protein kinase superfamily, Tyr protein kinase family
Tissue Specificity Expressed in colon, skin, lung and bone marrow.
Buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form Liquid
Format Liquid
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Storage Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications WB, ELISA
Description WB ; ELISA
Dilution

WB1:500-1:2000
ELISA1:40000
Tested Application WB,ELISA;WB:1/500-1/2000.ELISA:1/40000
Datasheet
Western Blotting(WB) Protocol
ELISA Protocol
SKU Supplier No. Size Your price Quantity
BHA10538945 CSB-PA010260 100μg $168.78
Add to Cart
BHA10538945 CSB-PA010260 50μg $123
Add to Cart