Phospho-MEKK1 (Thr1402)[Thr1400] Antibody

Mfr.No.	DF8741
Alternative Names	M3K1_HUMAN ; MAP3K1 ; MAPK/ERK kinase kinase 1 ; MAPKKK1 ; MEK kinase 1 ; MEKK 1 ; Mekk ; MEKK1 ; Mitogen activated protein kinase kinase kinase 1 ; Mitogen activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase ; Mitogen-activated protein kinase kinase kinase 1 ; SRXY6 ;
Categories	Primary Antibodies ; Phospho Antibodies
Clonality	polyclonal
Immunogen	A synthesized peptide derived from human Phospho-MAP3K1 (Thr1402).
Molecular Weight	Observed Mol.Wt.: 161 kDa. Predicted Mol.Wt.: 165kDa.
Reactivity	Human, Mouse, Rat
Specificity	Phospho-MAP3K1 (Thr1402) Antibody detects endogenous levels of MAP3K1 only when phosphorylated at Thr1402.

Uniprot

Q13233

Gene Id

4214

Sequence

10 20 30 40 50
MAAAAGNRAS SSGFPGARAT SPEAGGGGGA LKASSAPAAA AGLLREAGSG
60 70 80 90 100
GRERADWRRR QLRKVRSVEL DQLPEQPLFL AASPPASSTS PSPEPADAAG
110 120 130 140 150
SGTGFQPVAV PPPHGAASRG GAHLTESVAA PDSGASSPAA AEPGEKRAPA
160 170 180 190 200
AEPSPAAAPA GREMENKETL KGLHKMDDRP EERMIREKLK ATCMPAWKHE
210 220 230 240 250
WLERRNRRGP VVVKPIPVKG DGSEMNHLAA ESPGEVQASA ASPASKGRRS
260 270 280 290 300
PSPGNSPSGR TVKSESPGVR RKRVSPVPFQ SGRITPPRRA PSPDGFSPYS
310 320 330 340 350
PEETNRRVNK VMRARLYLLQ QIGPNSFLIG GDSPDNKYRV FIGPQNCSCA
360 370 380 390 400
RGTFCIHLLF VMLRVFQLEP SDPMLWRKTL KNFEVESLFQ KYHSRRSSRI
410 420 430 440 450
KAPSRNTIQK FVSRMSNSHT LSSSSTSTSS SENSIKDEEE QMCPICLLGM
460 470 480 490 500
LDEESLTVCE DGCRNKLHHH CMSIWAEECR RNREPLICPL CRSKWRSHDF
510 520 530 540 550
YSHELSSPVD SPSSLRAAQQ QTVQQQPLAG SRRNQESNFN LTHYGTQQIP
560 570 580 590 600
PAYKDLAEPW IQVFGMELVG CLFSRNWNVR EMALRRLSHD VSGALLLANG
610 620 630 640 650
ESTGNSGGSS GSSPSGGATS GSSQTSISGD VVEACCSVLS MVCADPVYKV
660 670 680 690 700
YVAALKTLRA MLVYTPCHSL AERIKLQRLL QPVVDTILVK CADANSRTSQ
710 720 730 740 750
LSISTLLELC KGQAGELAVG REILKAGSIG IGGVDYVLNC ILGNQTESNN
760 770 780 790 800
WQELLGRLCL IDRLLLEFPA EFYPHIVSTD VSQAEPVEIR YKKLLSLLTF
810 820 830 840 850
ALQSIDNSHS MVGKLSRRIY LSSARMVTTV PHVFSKLLEM LSVSSSTHFT
860 870 880 890 900
RMRRRLMAIA DEVEIAEAIQ LGVEDTLDGQ QDSFLQASVP NNYLETTENS
910 920 930 940 950
SPECTVHLEK TGKGLCATKL SASSEDISER LASISVGPSS STTTTTTTTE
960 970 980 990 1000
QPKPMVQTKG RPHSQCLNSS PLSHHSQLMF PALSTPSSST PSVPAGTATD
1010 1020 1030 1040 1050
VSKHRLQGFI PCRIPSASPQ TQRKFSLQFH RNCPENKDSD KLSPVFTQSR
1060 1070 1080 1090 1100
PLPSSNIHRP KPSRPTPGNT SKQGDPSKNS MTLDLNSSSK CDDSFGCSSN
1110 1120 1130 1140 1150
SSNAVIPSDE TVFTPVEEKC RLDVNTELNS SIEDLLEASM PSSDTTVTFK
1160 1170 1180 1190 1200
SEVAVLSPEK AENDDTYKDD VNHNQKCKEK MEAEEEEALA IAMAMSASQD
1210 1220 1230 1240 1250
ALPIVPQLQV ENGEDIIIIQ QDTPETLPGH TKAKQPYRED TEWLKGQQIG
1260 1270 1280 1290 1300
LGAFSSCYQA QDVGTGTLMA VKQVTYVRNT SSEQEEVVEA LREEIRMMSH
1310 1320 1330 1340 1350
LNHPNIIRML GATCEKSNYN LFIEWMAGGS VAHLLSKYGA FKESVVINYT
1360 1370 1380 1390 1400
EQLLRGLSYL HENQIIHRDV KGANLLIDST GQRLRIADFG AAARLASKGT
1410 1420 1430 1440 1450
GAGEFQGQLL GTIAFMAPEV LRGQQYGRSC DVWSVGCAII EMACAKPPWN
1460 1470 1480 1490 1500
AEKHSNHLAL IFKIASATTA PSIPSHLSPG LRDVALRCLE LQPQDRPPSR
1510
ELLKHPVFRT TW

Concentration	1mg/ml
Format	Liquid
Purification	The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Storage Condition	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.