Phospho-ATF2 (Thr69/Thr51) Antibody

Mfr.No.	AF3178
Alternative Names	Activating transcription factor 2 ; Activating transcription factor 2 splice variant ATF2 var2 ; ATF 2 ; Atf-2 ; Atf2 ; ATF2 protein ; ATF2_HUMAN ; cAMP Response Element Binding Protein 2 ; cAMP response element binding protein CRE BP1 ; cAMP response element-binding protein CRE-BP1 ; cAMP responsive element binding protein 2, formerly ; cAMP-dependent transcription factor ATF-2 ; cAMP-responsive element-binding protein 2 ; CRE BP1 ; CRE-BP ; CREB 2 ; CREB-2 ; CREB2 ; CREBP1 ; Cyclic AMP dependent transcription factor ATF 2 ; Cyclic AMP-dependent transcription factor ATF-2 ; Cyclic AMP-responsive element-binding protein 2 ; D130078H02Rik ; D18875 ; HB 16 ; HB16 ; Histone acetyltransferase ATF2 ; MGC105211 ; MGC105222 ; MGC111558 ; MGC142504 ; mXBP ; MXBP protein ; Tg(Gzma-Klra1)7Wum ; TREB 7 ; TREB7 ;
Antigen	Phospho-ATF2 (Thr69/51)
Categories	Primary Antibodies ; Phospho Antibodies
Clonality	polyclonal
Description	This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro;
Immunogen	A synthesized peptide derived from human ATF2 around the phosphorylation site of Threonine 69 or 51.
Molecular Weight	Observed Mol.Wt.: 52kDa. Predicted Mol.Wt.: 55kDa.
Reactivity	Human, Mouse, Rat
Specificity	Phospho-ATF2 (Thr69 or 51) Antibody detects endogenous levels of ATF2 only when phosphorylated at Threonine 69 or 51.
Subcellular Location	Nucleus.

Uniprot

P15336

Gene Id

1386

Sequence

10	20	30	40	50
MKFKLHVNSA	RQYKDLWNMS	DDKPFLCTAP	GCGQRFTNED	HLAVHKHKHE
60	70	80	90	100
MTLKFGPARN	DSVIVADQTP	TPTRFLKNCE	EVGLFNELAS	PFENEFKKAS
110	120	130	140	150
EDDIKKMPLD	LSPLATPIIR	SKIEEPSVVE	TTHQDSPLPH	PESTTSDEKE
160	170	180	190	200
VPLAQTAQPT	SAIVRPASLQ	VPNVLLTSSD	SSVIIQQAVP	SPTSSTVITQ
210	220	230	240	250
APSSNRPIVP	VPGPFPLLLH	LPNGQTMPVA	IPASITSSNV	HVPAAVPLVR
260	270	280	290	300
PVTMVPSVPG	IPGPSSPQPV	QSEAKMRLKA	ALTQQHPPVT	NGDTVKGHGS
310	320	330	340	350
GLVRTQSEES	RPQSLQQPAT	STTETPASPA	HTTPQTQSTS	GRRRRAANED
360	370	380	390	400
PDEKRRKFLE	RNRAAASRCR	QKRKVWVQSL	EKKAEDLSSL	NGQLQSEVTL
410	420	430	440	450
LRNEVAQLKQ	LLLAHKDCPV	TAMQKKSGYH	TADKDDSSED	ISVPSSPHTE
460	470	480	490	500
AIQHSSVSTS	NGVSSTSKAE	AVATSVLTQM	ADQSTEPALS	QIVMAPSSQS

QPSGS

Concentration	1mg/ml
Format	Liquid
Purification	The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Storage Condition	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.