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Home / Antibodies

PE/Cyanine7 Anti-Mouse CD206 Antibody[C068C2]

SKU : BHA10325828

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	E-AB-F1135H
Background	CD206, also known as mannose receptor (MR), is a 175 kD type I membrane protein. It is a pattern recognition receptor (PRR) belonging to the C-type lectin superfamily. MR is expressed on macrophages, dendritic cells, Langerhans cells, and hepatic or lymphatic endothelial cells. MR recognizes a range of microbial carbohydrates bearing mannose, fucose, or N-acetyl glucosamine through its C-type lectin-like carbohydrate recognition domains, sulfated carbohydrate antigens through its cysteine-rich domain, and collagens through its fibronectin type II domain. MR mediates endocytosis and phagocytosis as well as activation of macrophages and antigen presentation. It plays an important role in host defense and provides a link between innate and adaptive immunity. Recently, MR on lymphatic endothelial cells was found to be involved in leukocyte trafficking and a contributor to the metastatic behavior of cancer cells. It suggests that MR may be a potential target in controlling inflammation and cancer metastasis by targeting the lymphatic vasculature.
Host	Rat
Immunogen	0
Isotype	Rat IgG2a, kappa
Reactivity	Mouse

Clone No	C068C2
Research Area	Cancer, Immunology

Buffer	PBS with 0.05% Proclin300, 1% BSA
Storage	Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Applications	ICFCM

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA10325828	E-AB-F1135H	20Tests	$75		Add to Cart
BHA10325828	E-AB-F1135H	50Tests	$115		Add to Cart
BHA10325828	E-AB-F1135H	100Tests	$185		Add to Cart
BHA10325828	E-AB-F1135H	200Tests	$275		Add to Cart

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