Rabbit Anti-Human PAK1 (pSer144) Polyclonal

Mfr.No.	SPC-1043, SPC-1043D, SPC-1043D-A390, SPC-1043D-A488, SPC-1043D-A594, SPC-1043D-BI, SPC-1043D-FITC
Immunogen Species	Human
Alternative Names	ADRB2 Antibody, Alpha PAK Antibody, Alpha-PAK Antibody, p21 activated kinase 1 Antibody, p21 protein (Cdc42/Rac) activated kinase 1 Antibody, p21-activated kinase 1 Antibody, p21/Cdc42/Rac1 activated kinase 1 (yeast Ste20 related) Antibody, p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast) Antibody, p65 PAK Antibody, p65-PAK Antibody, P68-PAK Antibody, PAK alpha Antibody, PAK-1 Antibody, Pak1 Antibody, PAK1_HUMAN Antibody, Paka Antibody, PAKalpha Antibody, Protein kinase MUK2 Antibody, Rac/p21-activated kinase Antibody, Serine/threonine-protein kinase PAK 1 Antibody, STE20 homolog yeast Antibody
Antigen	PAK1
Categories	Antibodies
Cellular Localization	Cytoplasm, Cell Junction, Focal Adhesion, Cell Membrane, Cell Projection, Invadopodium
Certificate Of Analysis	A 1:250 dilution of SPC-1043 was sufficient for detection of PAK1 (pSer144) in 10 ug of 293T cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
Clonality	Polyclonal
Conjugate	Unconjugated, ATTO 390, ATTO 488, ATTO 594, Biotin, FITC
Description	Rabbit Anti-Human PAK1 (pSer144) Polyclonal
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Host	Rabbit
Gross Weight (kg)	1.4
Immunogen	A phospho-specific peptide corresponding to residues surrounding Ser144 of human PAK1 (AA141-147), Homo Sapiens (Human)
Immunogen Region	A phospho-specific peptide corresponding to residues surrounding Ser144 of human PAK1 (AA141-147)
Launch Date	2016/08/29
Net Weight (g)	0.1
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)
Species Reactivity Medium	Human
Tissue Specificity	Highly expressed in the brain and blood cells. Overexpressed in gastric cancer cells and tissues.

Swissprot	Q13153
Accession Number	NP_002567
Gene Id	5058
Target	PAK1 (pSer144)
Research Area	Cancer, Apoptosis, Intracellular, Cell Signaling, Protein Phosphorylation, Serine / Threonine Kinases

Buffer	PBS pH7.4, 50% glycerol, 0.025% Thimerosal
Dilutions	WB (1:250); optimal dilutions for assays should be determined by the user.
Purification	Peptide Affinity Purified
Purity	Highly expressed in the brain and blood cells. Overexpressed in gastric cancer cells and tissues.
Scientific Background	PAK1 is a protein-serine/threonine kinase. Pak1 binds to activated forms of the GTPases Cdc42 and Rac. Upon binding to Cdc42 or Rac, Pak1 is activated and autophosphorylates. Pak1 has dozens of substrates, activating cytoskeletal and transcription pathways that enhance cell motility, proliferation, and survival.
Shipping Temperature	Blue Ice or 4°C
Specificity	Detects 60.661 kDa.
Storage	-20ºC
Storage Buffer	PBS pH7.4, 50% glycerol, 0.025% Thimerosal *Storage buffer may change when conjugated
Storage Temperature	-20°C

Applications	AM, WB
Description	WB ; AM
Dilution	WB (1:250); optimal dilutions for assays should be determined by the user.

Product Manual	SDS
SDS

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Combination SKU	Supplier No.	Conjugate	Size	Your price
BHA11913590-1	SPC-1043D	Unconjugated	100 ul	$331	Add to Cart
BHA11913590-2	SPC-1043D-A390	ATTO 390	100 ul	$385	Add to Cart
BHA11913590-3	SPC-1043D-A488	ATTO 488	100 ul	$384	Add to Cart
BHA11913590-4	SPC-1043D-A594	ATTO 594	100 ul	$384	Add to Cart
BHA11913590-5	SPC-1043D-BI	Biotin	100 ul	$380	Add to Cart
BHA11913590-6	SPC-1043D-FITC	FITC	100 ul	$375	Add to Cart

PAK1 Antibody (pSer144) - SPC-1043

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