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Home / Primary Antibodies / Polyclonal Antibodies

p70S6K antibody

SKU : BHA10806082

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Mfr.No.	FNab06090
Alternative Names	P70alpha ; p70ribosomalS6kinasealpha ; p70S6kinasealpha ; p70S6K1 ; p70S6Kalpha ; p70S6KA ; p70(S6K)alpha ; p70S6K ; P70S6K1 ; PS6K ; RibosomalproteinS6kinaseI
Background	RPS6KB1(Ribosomal protein S6 kinase beta-1) is also named as STK14A, p70 S6KA and belongs to the S6 kinase subfamily. RPS6KB1 is a major substrate of MTOR and acts as a crucial effector of MTOR signaling pathway and it plays a key role in cell growth and proliferation by regulating insulin sensitivity, metabolism, protein synthesis, and cell cycle. RPS6KB1 may play an important role in the progression of HCC and could serve as a potential molecular target for HCC therapy.(PMID:22684641). It has 2 isoforms produced by alternative initiation.
Categories	Primary Antibodies
Cellular Localization	Cell Junction, Cytoplasm, Membrane, Mitochondria, Mitochondrion Outer Membrane, Nucleus, Synapse, Synaptosome
Clonality	polyclonal
Description	RPS6KB1(Ribosomal protein S6 kinase beta-1) is also named as STK14A, p70 S6KA and belongs to the S6 kinase subfamily. RPS6KB1 is a major substrate of MTOR and acts as a crucial effector of MTOR signaling pathway and it plays a key role in cell growth and proliferation by regulating insulin sensitivity, metabolism, protein synthesis, and cell cycle. RPS6KB1 may play an important role in the progression of HCC and could serve as a potential molecular target for HCC therapy.(PMID:22684641). It has 2 isoforms produced by alternative initiation.
Host	Rabbit
Immunogen	ribosomal protein S6 kinase, 70kDa, polypeptide 1
Isotype	IgG
Molecular Weight	65-70 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Subcellular Location	Cell junction, Cytoplasm, Membrane, Mitochondrion, Mitochondrion outer membrane, Nucleus, Synapse, Synaptosome
Synonyms	P70 alpha, p70 ribosomal S6 kinase alpha, p70 S6 kinase alpha, p70 S6K 1, p70 S6K alpha, p70 S6KA, p70(S6K) alpha, p70S6K, P70S6K1, PS6K, Ribosomal protein S6 kinase I, RPS6KB1, S6K, S6K beta 1, S6K1, STK14A

Uniprot	P23443
Gene Id	6198
Weight	59kDa,observed 70kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC, IF, IP, FC

Description

ELISA ; WB ; IHC ; IF ; IP ; FC

Dilution

WB	1:500-1:5000
IP	1:500-1:5000
IHC	1:100-1:400
IF	1:10-1:100

Tested Application

WB: 1:500-1:5000; IP: 1:500-1:5000; IHC: 1:100-1:400; IF: 1:10-1:100

Manual	FNab06090.pdf

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA10806082	FNab06090	100ug	$260		Add to Cart

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