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Home / Antibodies

p70 S6 Kinase alpha Antibody (RPS6KB1) (phospho-S418) (F48493)

SKU : BHA17101247

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NSJ Bioreagents

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Mfr.No.	F48493, F48493-0.08ML, F48493-0.4ML
Clonality	Polyclonal
Description	p70 S6K is a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein leads to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding this gene and overexpression of this kinase are seen in some breast cancer cell lines. Alternate translational start sites have been described and alternate transcriptional splice variants have been observed but have not been thoroughly characterized.
Formulation	In 1X PBS, pH 7.4, with 0.09% sodium azide
Host	Rabbit
Immunogen Region	This phospho-S6K antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS418 of human RPS6KB1.
Isotype	Ig
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No

Uniprot	P23443

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	Aliquot the phospho-S6K antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Applications	DB, ELISA
Dilution	Dot blot: 1:500

Product Manual	Data Sheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17101247-1	F48493-0.08ML	0.08ml	$165		Add to Cart
BHA17101247-2	F48493-0.4ML	0.4ml	$379		Add to Cart

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