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Home / Antibodies

ORC4 Antibody

BHA10547056
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Rgd 735212
Target Details The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. This protein is a subunit of the ORC complex. It has been shown to form a core complex with ORC2L, -3L, and -5L. Three alternatively spliced transcript variants encoding the same protein have been reported.
Uniprot O43929
Database Links

HGNC:8490

OMIM:603056

KEGG:hsa:5000

STRING:9606.ENSP00000264169

UniGene:Hs.558364
Function Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3.
Pathway Cell cycle
Protein Families ORC4 family
Research Area Transcription
Buffer PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20℃, Avoid freeze / thaw cycles.
Format Liquid
Purification Antigen Affinity Purified
Purity Antigen Affinity Purified
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Storage Buffer

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Applications ELISA, WB
Description ELISA ; WB, WB ; ELISA
Tested Application ELISA,WB
Datasheet
ELISA Protocol
Western Blotting(WB) Protocol
SKU Supplier No. Size Your price Quantity
BHA10547056 CSB-PA017234GA01HU 150μl $610.56
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BHA10547056 CSB-PA017234GA01HU 50μl $269.50
Add to Cart