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Home / Primary Antibodies / Polyclonal Antibodies

NT5E/CD73 antibody

SKU : BHA10805870

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Mfr.No.	FNab05878
Background	NT5E(5'-nucleotidase) is also named as NT5, NTE,CD73,ecto-5'-nucleotidase, and belongs to the 5'-nucleotidase family. It catalyzes the conversion at neutral pH of purine 5-prime mononucleotides to nucleosides, the preferred substrate being AMP.The enzyme occurs mainly as a dimer and the wide distribution of NT5E in the rat hippocampus, suggesting their involvement in the control of the purinergic signaling(PMID:17619139). This protein has two isoforms with the molecular weight of 63 kDa and 58 kDa and four glycosylation sites with a signalpeptide. It can exsit as a dimer(PMID:17619139). It can be detected the band of 55 kDa,64 kDa, 70 kDa, 110 kDa by western blot(PMID:17619139; 12370277; 21533188). Defects in NT5E are the cause of calcification of joints and arteries(CALJA).
Categories	Primary Antibodies
Clonality	polyclonal
Host	Rabbit
Immunogen	5'-nucleotidase, ecto(CD73)
Isotype	IgG
Molecular Weight	63 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	5 NT, 5 nucleotidase, 5' nucleotidase, ecto(CD73), CD73, E5NT, Ecto 5 nucleotidase, eN, eNT, NT, NT5, NT5E, NTE

Uniprot	P21589
Gene Id	4907
Research Area	Metabolism, Cardiovascular, Immunology, Cancer, Stem Cells

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB
Description	ELISA ; WB
Tested Application	WB: 1:500-1:5000; IHC: 1:50-1:500

Manual	FNab05878.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10805870	FNab05878	100ug	$260		Add to Cart

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