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Home / Primary Antibodies / Polyclonal Antibodies

NOTCH3 antibody

SKU : BHA10805792

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Mfr.No.	FNab05800
Background	Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain(NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs(By similarity).
Categories	Primary Antibodies
Clonality	polyclonal
Description	Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs (By similarity).
Host	Rabbit
Immunogen	Notch homolog 3
Isotype	IgG
Molecular Weight	250-260 kDa, 100 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	CADASIL, CASIL, Notch 3, Notch homolog 3, NOTCH3

Uniprot	Q9UM47
Gene Id	4854
Research Area	Developmental biology, Signal Transduction, Metabolism, Cardiovascular, Immunology

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC, IP
Description	ELISA ; WB ; IHC ; IP
Tested Application	WB: 1:500-1:2000; IP: 1:500-1:1000; IHC: 1:50-1:500

Manual	FNab05800.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10805792	FNab05800	100ug	$240		Add to Cart

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