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Home / Primary Antibodies / Polyclonal Antibodies

NELFE antibody

SKU : BHA10805650

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Mfr.No.	FNab05658
Alternative Names	RD ; RDBP
Background	The protein encoded by this gene is part of a complex termed negative elongation factor (NELF) which represses RNA polymerase II transcript elongation. This protein bears similarity to nuclear RNA-binding proteins; however, it has not been demonstrated that this protein binds RNA. The protein contains a tract of alternating basic and acidic residues, largely arginine (R) and aspartic acid (D). The gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex.
Host	Rabbit
Immunogen	RD RNA binding protein
Isotype	IgG
Molecular Weight	43 kDa
Reactivity	Human, Mouse
Regulatory	RUO
Synonyms	RD, RDBP

Uniprot	P18615
Gene Id	7936
Research Area	Developmental biology, Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC, IP
Description	ELISA ; WB ; IHC ; IP
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

Manual	FNab05658.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10805650	FNab05658	100ug	$260		Add to Cart

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