Protein kinase which plays an important role in the G2/M checkpoint response to DNA damage. Controls degradation of CDC25A by directly phosphorylating it on residues whose phosphorylation is required for BTRC-mediated polyubiquitination and degradation.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Protein kinase which plays an important role in the G2/M checkpoint response to DNA damage. Controls degradation of CDC25A by directly phosphorylating it on residues whose phosphorylation is required for BTRC-mediated polyubiquitination and degradation.
Host
Rabbit
Immunogen
NIMA(never in mitosis gene a)-related kinase 11
Isotype
IgG
Molecular Weight
54kd
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Uniprot
Q8NG66
Gene Id
79858
Research Area
Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)