Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes, such as CCND1, and may thereby act as tumor suppressor. May be involved in dendritic cell and neuron differentiation.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes, such as CCND1, and may thereby act as tumor suppressor. May be involved in dendritic cell and neuron differentiation.
Host
Rabbit
Immunogen
NDRG family member 2
Isotype
IgG
Molecular Weight
41-43 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
KIAA1248, SYLD
Uniprot
Q9UN36
Gene Id
57447
Research Area
Cell Division and Proliferation, Developmental biology, Signal Transduction, Neuroscience
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)