NCOR1, also named as KIAA1047 and TRAC1, belongs to the N-CoR nuclear receptor corepressors family. NCO1 mediates transcriptional repression by certain nuclear receptors. It is part of a complex which promotes histone deacetylation and the formation of repressive chromatin structures which may impede the access of basal transcription factors. The antibody recognizes the N-term of NCOR1.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Mediates transcriptional repression by certain nuclear receptors. Part of a complex which promotes histone deacetylation and the formation of repressive chromatin structures which may impede the access of basal transcription factors. Participates in the transcriptional repressor activity produced by BCL6.
Host
Rabbit
Immunogen
nuclear receptor co-repressor 1
Isotype
IgG
Molecular Weight
120kd
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
hCIT529I10, hN CoR, KIAA1047, N CoR, N CoR1, NCOR1, Nuclear receptor corepressor 1, TRAC1
Uniprot
O75376
Gene Id
9611
Research Area
Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)