Rabbit Anti-Human MEK4 Polyclonal

Mfr.No.	SPC-1170, SPC-1170D, SPC-1170D-A390, SPC-1170D-A488, SPC-1170D-A594, SPC-1170D-BI, SPC-1170D-FITC
Immunogen Species	Human
Alternative Names	C-JUN N-terminal kinase kinase 1 antibody, Dual specificity mitogen activated protein kinase kinase 4 antibody, Dual specificity mitogen-activated protein kinase kinase 4 antibody, JNK Activated Kinase 1 antibody, JNKK antibody, JNKK1 antibody, MAP kinase kinase 4 antibody, Map2k4 antibody, MAPK ERK kinase 4 antibody, MAPK/ERK kinase 4 antibody, MAPKK 4 antibody, MEK 4 antibody, MEK4 antibody, Mitogen activated protein kinase kinase 4 antibody, MKK4 antibody, MP2K4_HUMAN antibody, PRKMK4 antibody, SAPK ERK kinase 1 antibody, SAPKK 1 antibody, SEK1 antibody, SERK1 antibody, SKK1 antibody, Stress activated protein kinase kinase 1 antibody
Categories	Antibodies
Cellular Localization	Cytoplasm, Nucleus
Certificate Of Analysis	A 1:250 dilution of SPC-1170 was sufficient for detection of MEK4 in 10 ug of HeLa cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
Clonality	Polyclonal
Description	Rabbit Anti-Human MEK4 Polyclonal
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Host	Rabbit
Gross Weight (kg)	1.4
Immunogen	Synthetic peptide of human MEK4 (AA323-337), Homo Sapiens (Human)
Immunogen Region	Synthetic peptide of human MEK4 (AA323-337)
Launch Date	2016/08/29
Net Weight (g)	0.1
Reactivity	Mouse, Human
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)
Species Reactivity Medium	Mouse, Human
Tissue Specificity	Abundant expression is seen in the skeletal muscle. It is also widely expressed in other tissues.

Swissprot	P45985
Accession Number	NP_003001
Gene Id	6416
Target	MEK4
Research Area	Cell Signaling, Protein Phosphorylation, Serine / Threonine Kinases, MAPK Pathway

Buffer	PBS pH7.4, 50% glycerol, 0.025% Thimerosal
Dilutions	WB (1:250); optimal dilutions for assays should be determined by the user.
Purification	Peptide Affinity Purified
Purity	Abundant expression is seen in the skeletal muscle. It is also widely expressed in other tissues.
Scientific Background	MAP2K4 is a protein-serine/threonine/tyrosine kinase. Involved in MAPK signalling in response to stressors or mitogens. It signals through JNK1/JNK2, ERK1/ERK2, p38 and more. It has arole in maintaining peripheral lymphoid homeostasis and apoptosis. Mutations and deletions of this genes leads to dysregulated JNK signalling and promotes oncogenesis.
Shipping Temperature	Blue Ice or 4°C
Specificity	Detects 44kDa.
Storage	-20ºC
Storage Buffer	PBS pH7.4, 50% glycerol, 0.025% Thimerosal *Storage buffer may change when conjugated
Storage Temperature	-20°C

Applications	AM, WB
Description	WB ; AM
Dilution	WB (1:250); optimal dilutions for assays should be determined by the user.

Product Manual	SDS
SDS

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Combination SKU	Supplier No.	Conjugate	Size	Your price
BHA11915876-1	SPC-1170D	Unconjugated	100 ul	$331	Add to Cart
BHA11915876-2	SPC-1170D-A390	ATTO 390	100 ul	$385	Add to Cart
BHA11915876-3	SPC-1170D-A488	ATTO 488	100 ul	$384	Add to Cart
BHA11915876-4	SPC-1170D-A594	ATTO 594	100 ul	$384	Add to Cart
BHA11915876-5	SPC-1170D-BI	Biotin	100 ul	$380	Add to Cart
BHA11915876-6	SPC-1170D-FITC	FITC	100 ul	$375	Add to Cart

MEK4 Antibody - SPC-1170

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