Receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. Promotes apoptosis via TRAF3 and TRAF5. May play a role in the development of lymphoid organs.Baens M., Genomics 16:214-218(1993).Crowe P.D., Science 264:707-710(1994).Wu M.-Y., J. Biol. Chem. 274:11868-11873(1999).
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human LTBR.
Raised In
Rabbit
Reactivity
Human, Mouse
Regulatory
RUO
Relevance
Receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. Promotes apoptosis via TRAF3 and TRAF5. May play a role in the development of lymphoid organs.
Baens M., Genomics 16:214-218(1993). Crowe P.D., Science 264:707-710(1994). Wu M.-Y., J. Biol. Chem. 274:11868-11873(1999).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total LTBR protein.
Receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. Promotes apoptosis via TRAF3 and TRAF5. May play a role in the development of lymphoid organs.
Pathway
HIF-1 signaling pathway NF-kappa B signaling pathway
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.