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Home / Antibodies

KRT10 Antibody / Cytokeratin 10 (V3633)

SKU : BHA17114423

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NSJ Bioreagents

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Mfr.No.	V3633, V3633-20UG, V3633-100UG
Clonality	Monoclonal
Description	This mAb recognizes a protein of 56.5kDa, identified as cytokeratin 10 (CK10). CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of CK10 strictly parallels the extent of differentiation; it is absent in the basal layer, appears in the first suprabasal layers and increases in concentration towards the granular layer. However, CK10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm, clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm, clinical stages II and III), CK10 is detected very frequently. Expression of CK10 is related to maturation of malignant keratinocytes, being preferentially detected in more-differentiated parts.
Formulation	0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Host	Rabbit
Immunogen Region	Skin extract from a Psoriasis patient was used as the immunogen for the recombinant Cytokeratin 10 antibody.
Isotype	IgG,kappa
Predicted Reactivity	Human, Mouse
Reactivity	Human, Mouse
Recombinant	Yes
Subcellular Location	Cytoplasmic

Uniprot	P13645
Clone No	KRT10/1990R

Concentration	0.2 mg/ml
Format	Purified
Purification	Protein A affinity chromatography
Storage	Store the recombinant Cytokeratin 10 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Applications	IHC-P
Dilution	Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT

Product Manual	Data Sheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17114423-1	V3633-20UG	20ug	$219		Add to Cart
BHA17114423-2	V3633-100UG	100ug	$499		Add to Cart

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