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Home / Primary Antibodies / Polyclonal Antibodies

KCNAB2 antibody

SKU : BHA10804471

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Mfr.No.	FNab04479
Alternative Names	KCNA2B ; KCNK2
Background	Cytoplasmic potassium channel subunit that modulates the characteristics of the channel-forming alpha-subunits(PubMed:7649300, PubMed:11825900). Contributes to the regulation of nerve signaling, and prevents neuronal hyperexcitability(By similarity). Promotes expression of the pore-forming alpha subunits at the cell membrane, and thereby increases channel activity(By similarity). Promotes potassium channel closure via a mechanism that does not involve physical obstruction of the channel pore(PubMed:7649300, PubMed:11825900). Promotes KCNA4 channel closure(PubMed:7649300, PubMed:11825900). Modulates the functional properties of KCNA5(By similarity). Enhances KCNB2 channel activity(By similarity). Binds NADPH and has NADPH-dependent aldoketoreductase activity(By similarity). Has broad substrate specificity and can catalyze the reduction of methylglyoxal, 9,10-phenanthrenequinone, prostaglandin J2, 4-nitrobenzaldehyde, 4-nitroacetophenone and 4-oxo-trans-2-nonenal(in vitro)(By similarity).
Categories	Primary Antibodies
Clonality	polyclonal
Description	Cytoplasmic potassium channel subunit that modulates the characteristics of the channel-forming alpha-subunits (PubMed:7649300, PubMed:11825900). Contributes to the regulation of nerve signaling, and prevents neuronal hyperexcitability (By similarity). Promotes expression of the pore-forming alpha subunits at the cell membrane, and thereby increases channel activity (By similarity). Promotes potassium channel closure via a mechanism that does not involve physical obstruction of the channel pore (PubMed:7649300, PubMed:11825900). Promotes KCNA4 channel closure (PubMed:7649300, PubMed:11825900). Modulates the functional properties of KCNA5 (By similarity). Enhances KCNB2 channel activity (By similarity). Binds NADPH and has NADPH- dependent aldoketoreductase activity (By similarity). Has broad substrate specificity and can catalyze the reduction of methylglyoxal, 9,10-phenanthrenequinone, prostaglandin J2, 4- nitrobenzaldehyde, 4-nitroacetophenone and 4-oxo-trans-2-nonenal (in vitro) (By similarity).
Host	Rabbit
Immunogen	potassium voltage-gated channel, shaker-related subfamily, beta member 2
Isotype	IgG
Molecular Weight	38kd
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	KCNA2B, KCNK2

Uniprot	Q13303
Gene Id	8514
Research Area	Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB
Description	ELISA ; WB
Tested Application	WB: 1:500 - 1:2000

Manual	FNab04479.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10804471	FNab04479	100ug	$240		Add to Cart

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