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Home / Antibodies

KAD6 Antibody

SKU : BHA12903419

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AFFINITY BIOSCIENCES LTD

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Mfr.No.	AF0683
Alternative Names	AD-004 ; Adenylate kinase isoenzyme 6 ; Adrenal gland protein AD-004 ; AK/ATPase ; AK6 ; CGI-137 ; CIP ; Coilin-interacting nuclear ATPase protein ; Dual activity adenylate kinase/ATPase ; hCINAP ; KAD6_HUMAN ; TAF9 ;
Categories	Primary Antibodies
Clonality	polyclonal
Description	Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the smaller subunits of TFIID that binds to the basal transcription factor GTF2B as well as to several transcriptional activators such as p53 and VP16. A similar but distinct gene (TAF9L) has been found on the X chromosome and a pseudogene has been identified on chromosome 19. Alternative splicing results in multiple transcript variants encoding different isoforms.
Immunogen	A synthesized peptide derived from human KAD6.
Molecular Weight	Observed Mol.Wt.: 20kDa. Predicted Mol.Wt.: 21kDa.
Reactivity	Human, Mouse, Rat
Specificity	KAD6 Antibody detects endogenous levels of KAD6.
Subcellular Location	Nucleus > nucleoplasm. Nucleus > Cajal body. Displays widespread diffuse nucleoplasmic distribution but not detected in nucleoli. Detected in Cajal bodies but not in all cells.

Uniprot

Q9Y3D8

Gene Id

102157402

Sequence

10	20	30	40	50
MLLPNILLTG	TPGVGKTTLG	KELASKSGLK	YINVGDLARE	EQLYDGYDEE
60	70	80	90	100
YDCPILDEDR	VVDELDNQMR	EGGVIVDYHG	CDFFPERWFH	IVFVLRTDTN
110	120	130	140	150
VLYERLETRG	YNEKKLTDNI	QCEIFQVLYE	EATASYKEEI	VHQLPSNKPE
160	170
ELENNVDQIL	KWIEQWIKDH	NS

Concentration	1mg/ml
Format	Liquid
Purification	The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage Condition	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.

Applications	IF/ICC, ELISA, WB
Dilution	WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Manual
MSDS
IF/ICC Protocol.
Western Blotting Handbook.

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SKU	Supplier No.	Size	Your price	Quantity
BHA12903419	AF0683	100ul	$280		Add to Cart
BHA12903419	AF0683	200ul	$350		Add to Cart

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