NOS2, also named as iNOS and NOS2A, produces nitric oxide(NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. NO is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. NOS2 is a nitric oxide synthase which is expressed in liver and is inducible by a combination of lipopolysaccharide and certain cytokines. This antibody is specific to NOS2.
Clonality
polyclonal
Host
Rabbit
Immunogen
nitric oxide synthase 2, inducible
Immunogen Region
nitric oXide synthase 2, inducible
Isotype
IgG
Reactivity
Human, Rat
Recommended Dilution
IHC: 1:20-1:200
Synonyms
HEP NOS, Hepatocyte NOS, Inducible NO synthase, Inducible NOS, INOS, NOS, NOS type II, NOS2, NOS2A
Uniprot
P35228
Gene Id
4843
Research Area
Signal Transduction, Metabolism, Neuroscience
Form
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
Tested Application
IHC: 1:20-1:200
Product Manual
<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10777.pdf" target="_blank">Data Sheet</ a>