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Home / Antibodies

IFT74 Antibody

SKU : BHA10555560

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA108409
Alternative Names	intraflagellar transport 74 homolog (Chlamydomonas)
Antigen	IFT74
Categories	Primary Antibodies
Conjugate	Non-conjugated
Description	Capillary morphogenesis protein 1 (CMG1), also known as intraflagellar transport protein 74 (ITP74) or coiled-coil domain-containing protein 2 (CCDC2), is a 600 amino acid human homologue of IFT-71, a complex B protein supporting intraflagellar transport (IFT) in Chlamydomonas. CMG1 localizes to the cytoplasmic vesicle and is highly expressed in adult and fetal kidney and testis, with lower levels of expression in adult heart, placenta, lung, liver and pancreas, and in fetal heart, lung and liver. CMG1 has been suggested to have a role in the primary cilia of HUVEC, and it also functions as a transcriptional regulator of cyclin D2 in spermatocyte-derived cells.
Host	Rabbit
Immunogen	Synthetic peptide of human IFT74
Involvement In Disease	Bardet-Biedl syndrome 20 (BBS20)
Isotype	IgG
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Capillary morphogenesis protein 1 (CMG1), also known as intraflagellar transport protein 74 (ITP74) or coiled-coil domain-containing protein 2 (CCDC2), is a 600 amino acid human homologue of IFT-71, a complex B protein supporting intraflagellar transport (IFT) in Chlamydomonas. CMG1 localizes to the cytoplasmic vesicle and is highly expressed in adult and fetal kidney and testis, with lower levels of expression in adult heart, placenta, lung, liver and pancreas, and in fetal heart, lung and liver. CMG1 has been suggested to have a role in the primary cilia of HUVEC, and it also functions as a transcriptional regulator of cyclin D2 in spermatocyte-derived cells.
Species	Homo Sapiens (Human)
Subcellular Location	Cell projection, cilium, Cytoplasmic vesicle

Uniprot	Q96LB3
Database Links	HGNC:21424 OMIM:608040 KEGG:hsa:80173 STRING:9606.ENSP00000369402 UniGene:Hs.145402
Function	Component of the intraflagellar transport (IFT) complex B
Protein Families	IFT74 family
Tissue Specificity	Highly expressed in adult and fetal kidney and expressed at lower level in adult heart, placenta, lung, liver and pancreas, and in fetal heart, lung and liver. Little to no expression was detected in adult brain and skeletal muscle or in fetal brain, thym

Buffer	-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form	Liquid
Format	Liquid
Purification	Antigen affinity purification
Purity	Antigen affinity purification
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Storage Buffer	-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

ELISA	1:2000-1:5000
WB	1:500-1:2000

Tested Application

ELISA,WB;ELISA:1:2000-1:5000,WB:1:500-1:2000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10555560	CSB-PA108409	100μl	$279.30		Add to Cart
BHA10555560	CSB-PA108409	50μl	$168		Add to Cart

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