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Home / Primary Antibodies / Polyclonal Antibodies

HNMT antibody

SKU : BHA10803938

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Mfr.No.	FNab03944
Background	In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Inactivates histamine by N-methylation. Plays an important role in degrading histamine and in regulating the airway response to histamine.
Host	Rabbit
Immunogen	histamine N-methyltransferase
Isotype	IgG
Molecular Weight	27 kDa
Reactivity	Human, Mouse
Regulatory	RUO
Synonyms	HMT

Uniprot	P50135
Gene Id	3176
Research Area	Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC, IF
Description	ELISA ; WB ; IHC ; IF
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IP : 1:20 - 1:50

Manual	FNab03944.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10803938	FNab03944	100ug	$260		Add to Cart

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