Rabbit Anti-Human HDAC1 Polyclonal

Mfr.No.	SPC-1324, SPC-1324D, SPC-1324D-A390, SPC-1324D-A488, SPC-1324D-A594, SPC-1324D-BI, SPC-1324D-FITC
Immunogen Species	Human
Alternative Names	DKFZp686H12203 antibody, GON 10 antibody, HD1 antibody, HDAC 1 antibody, HDAC1 antibody, HDAC1_HUMAN antibody, Histone deacetylase 1 antibody, Reduced potassium dependency yeast homolog like 1 antibody, RPD3 antibody, RPD3L1 antibody
Categories	Antibodies
Cellular Localization	Nucleus
Certificate Of Analysis	A 1:1000 dilution of SPC-1324 was sufficient for detection of HDAC1 in 10 ug of NIH/3T3 cell lysates by ECL immunoblot analysis using Goat Anti-Rabbit IgG:HRP as the secondary antibody.
Clonality	Polyclonal
Description	Rabbit Anti-Human HDAC1 Polyclonal
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Host	Rabbit
Gross Weight (kg)	1.4
Immunogen	Synthesized peptide derived from Human HDAC1., Homo Sapiens (Human)
Immunogen Region	Synthesized peptide derived from human HDAC1.
Isotype	IgG
Launch Date	2016/09/06
Net Weight (g)	0.1
Reactivity	Rat, Mouse, Human
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)
Species Reactivity Medium	Mouse, Rat, Human

Swissprot	Q13547
Accession Number	NP_004955.2
Gene Id	3065
Target	HDAC1
Research Area	Stem Cell HDACs \|Cardiovascular System, Cell Signaling, Post-translational Modifications, Acetylation, Stem Cells, Heart, Hypertrophy

Buffer	PBS pH 7.4, 50% glycerol, 150mM NaCl, 0.02% sodium azide
Dilutions	WB (1:1000), IHC (1:100), ICC/IF (1:500), ELISA (1:10000); optimal dilutions for assays should be determined by the user.
Purification	Peptide Affinity Purified
Scientific Background	Histone deacetylase 1 is an enzyme that in humans is encoded by the HDAC1 gene. Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
Shipping Temperature	Blue Ice or 4°C
Specificity	Detects endogenous levels of total HDAC1 protein.
Storage	-20ºC
Storage Buffer	PBS pH 7.4, 50% glycerol, 150mM NaCl, 0.02% sodium azide *Storage buffer may change when conjugated
Storage Temperature	-20°C

Applications	ELISA, IHC, WB, ICC/IF
Description	WB ; IHC ; ICC ; IF ; ELISA
Dilution	WB (1:1000), IHC (1:100), ICC/IF (1:500), ELISA (1:10000); optimal dilutions for assays should be determined by the user.

Product Manual	SDS
SDS

Reference	1. Taunton J. et al. (1996) Science 272 (5260): 40811. 2. Gerdin AK. (2010) Acta Ophthalmologica 88 (S248).

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Combination SKU	Supplier No.	Conjugate	Size	Your price
BHA11918018-1	SPC-1324D	Unconjugated	100 ul	$286	Add to Cart
BHA11918018-2	SPC-1324D-A390	ATTO 390	100 ul	$340	Add to Cart
BHA11918018-3	SPC-1324D-A488	ATTO 488	100 ul	$339	Add to Cart
BHA11918018-4	SPC-1324D-A594	ATTO 594	100 ul	$339	Add to Cart
BHA11918018-5	SPC-1324D-BI	Biotin	100 ul	$334	Add to Cart
BHA11918018-6	SPC-1324D-FITC	FITC	100 ul	$330	Add to Cart

HDAC1 Antibody - SPC-1324