This gene encodes a multifunctional Ser/Thr protein kinase that is implicated in the control of several regulatory proteins including glycogen synthase, and transcription factors, such as JUN. It also plays a role in the WNT and PI3K signaling pathways, as well as regulates the production of beta-amyloid peptides associated with Alzheimer's disease.
Clonality
polyclonal
Host
Rabbit
Immunogen
glycogen synthase kinase 3 alpha
Immunogen Region
glycogen synthase kinase 3 alpha
Isotype
IgG
Molecular Weight
51 kDa
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:500 - 1:2000
Synonyms
GSK3 alpha, GSK3A
Uniprot
P49840
Gene Id
2931
Research Area
Developmental biology, Cell Division and Proliferation, Signal Transduction, Metabolism, Cardiovascular, Immunology, Neuroscience
Form
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Application
WB: 1:500 - 1:2000
Product Manual
<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10243.pdf" target="_blank">Data Sheet</ a>