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Home / Antibodies

Glycoprotein 2 Antibody / GP2 / ZAP75 (V7816)

SKU : BHA17117030

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NSJ Bioreagents

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Mfr.No.	V7816, V7816-20UG, V7816-100UG
Clonality	Monoclonal
Description	GP2 (glycoprotein 2), also known as ZAP75, is a 537 amino acid secreted protein. It is an integral membrane protein that is secreted from intracellular zymogen granules and associates with the plasma membrane via glycosylphosphatidylinositol (GPI) linkage. GP2 is cleaved and then released into the pancreatic duct along with exocrine secretions. GP2 binds pathogens such as enterobacteria, thereby playing an important role in the innate immune response. The C-terminus of this protein is related to the C-terminus of the protein encoded by the neighboring gene, uromodulin (UMOD). GP2 is also expressed on the apical plasma membrane of specialized microfold (M) cells among enterocytes and serves as a transcytotic receptor for mucosal antigens. M cells are considered a promising target for oral vaccination against various infectious diseases.
Formulation	0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Host	Mouse
Immunogen Region	A recombinant human partial protein (amino acids 35-179) was used as the immunogen for this Glycoprotein 2 antibody.
Isotype	IgG2c,kappa
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No
Subcellular Location	Cytoplasmic, membranous, secreted

Uniprot	P55259
Clone No	GP2/3416

Concentration	0.2 mg/ml
Format	Purified
Purification	Protein G affinity chromatography
Storage	Store the Glycoprotein 2 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Applications	WB, IHC-P
Dilution	Western blot: 1-2ug/ml,Immunohistochemistry: 1-2ug/ml

Product Manual	Data Sheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17117030-1	V7816-20UG	20ug	$219		Add to Cart
BHA17117030-2	V7816-100UG	100ug	$499		Add to Cart

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