Rabbit Anti-Human GIT1 (pTyr545) Polyclonal

Mfr.No.	SPC-987, SPC-987D, SPC-987D-A390, SPC-987D-A488, SPC-987D-A594, SPC-987D-BI, SPC-987D-FITC
Immunogen Species	Human
Alternative Names	ARF GAP GIT1 Antibody, ARF GTPase activating protein GIT1 Antibody, GIT1 Antibody, Cool associated and tyrosine phosphorylated protein 1 Antibody, G protein coupled receptor kinase interactor 1 Antibody, GRK interacting protein 1 Antibody
Categories	Antibodies
Cellular Localization	Aggresome, Cytoplasm, Cytosol, Focal Adhesion, Membrane
Certificate Of Analysis	A 1:250 dilution of SPC-987 was sufficient for detection of GIT1 (pTyr545) in 10 ug of HeLa cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
Clonality	Polyclonal
Description	Rabbit Anti-Human GIT1 (pTyr545) Polyclonal
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Host	Rabbit
Gross Weight (kg)	1.4
Immunogen	A phospho-specific peptide corresponding to residues surrounding Tyr545 of human GIT1 (AA542-548), Homo Sapiens (Human)
Immunogen Region	A phospho-specific peptide corresponding to residues surrounding Tyr545 of human GIT1 (AA542-548)
Launch Date	2016/08/29
Net Weight (g)	0.1
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)
Species Reactivity Medium	Human

Swissprot	Q9Y2X7
Accession Number	NP_001078923
Gene Id	28964
Target	GIT1 (pTyr545)
Research Area	Cell Signaling, Vesicle Transport, G Protein Signaling, GPCR, Protein Trafficking

Buffer	PBS pH7.4, 50% glycerol, 0.025% Thimerosal
Dilutions	WB (1:250); optimal dilutions for assays should be determined by the user.
Purification	Peptide Affinity Purified
Scientific Background	G-protein-coupled receptor kinase interactor 1 (GIT1) and G-protein-coupled receptor kinase interactor 2 (GIT2) are GTPase-activating proteins for ADP-ribosylation (Arf) GTPases. GIT1 and GIT2 regulate Arf activity and the sequestration of activated G protein-coupled receptors from the surface of the cell. These activities have effects on multiple cellular processes such as cell migration, T-cell activation, and centrosome dynamics. Both GIT proteins also serve as scaffolds to link signaling molecules. Alternative names for GIT1 include GRK-interacting protein 1, cool-associated and tyrosine phosphorylated protein 1, and Cat-1.
Shipping Temperature	Blue Ice or 4°C
Specificity	Detects 84.341 kDa.
Storage	-20ºC
Storage Buffer	PBS pH7.4, 50% glycerol, 0.025% Thimerosal *Storage buffer may change when conjugated
Storage Temperature	-20°C

Applications	AM, WB
Description	WB ; AM
Dilution	WB (1:250); optimal dilutions for assays should be determined by the user.

Product Manual	SDS
SDS

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Combination SKU	Supplier No.	Conjugate	Size	Your price
BHA11912582-1	SPC-987D	Unconjugated	100 ul	$331	Add to Cart
BHA11912582-2	SPC-987D-A390	ATTO 390	100 ul	$385	Add to Cart
BHA11912582-3	SPC-987D-A488	ATTO 488	100 ul	$384	Add to Cart
BHA11912582-4	SPC-987D-A594	ATTO 594	100 ul	$384	Add to Cart
BHA11912582-5	SPC-987D-BI	Biotin	100 ul	$380	Add to Cart
BHA11912582-6	SPC-987D-FITC	FITC	100 ul	$375	Add to Cart

GIT1 Antibody (pTyr545) - SPC-987