Growth arrest-specific protein 2 is a protein that in humans is encoded by the GAS2 gene. The protein encoded by this gene is a caspase-3 substrate that plays a role in regulating microfilament and cell shape changes during apoptosis. It can also modulate cell susceptibility to p53-dependent apoptosis by inhibiting calpain activity. Alternative splicing results in multiple transcript variants.
Host
Rabbit
Immunogen Region
Amino acids HQYSQWLASRHEANLLPMKED from the human protein were used as the immunogen for the GAS2 antibody.
Isotype
Rabbit IgG
Reactivity
Human, Mouse, Rat
Recombinant
No
Uniprot
O43903
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Concentration
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format
Antigen affinity purified
Purification
Antigen affinity purified
Storage
After reconstitution, the GAS2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Applications
WB, FACS
Dilution
Western blot: 1-2ug/ml,Flow cytometry: 1-3ug/million cells
Reviews of GAS2 Antibody / Growth arrest-specific protein 2 (RQ6872)