May play an important role in cell fate determination during lung development and in spermatogenesis By similarity.Pelletier G.J., Am. J. Physiol. 274:L351-L359(1998).Murphy D.B., Genomics 40:462-469(1997).Li C.-S., J. Hum. Genet. 51:292-297(2006).
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human FOXJ1.
Involvement In Disease
Allergic rhinitis (ALRH)
Raised In
Rabbit
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Relevance
May play an important role in cell fate determination during lung development and in spermatogenesis By similarity.
Pelletier G.J., Am. J. Physiol. 274:L351-L359(1998). Murphy D.B., Genomics 40:462-469(1997). Li C.-S., J. Hum. Genet. 51:292-297(2006).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total FOXJ1 protein.
Transcription factor specifically required for the formation of motile cilia. Acts by activating transcription of genes that mediate assembly of motile cilia, such as CFAP157. Binds the DNA consensus sequences 5'-HWDTGTTTGTTTA-3' or 5'-KTTTGTTGTTKTW-3' (where H is not G, W is A or T, D is not C, and K is G or T).
Protein Families
FOXJ1 family
Tissue Specificity
Testis, oviduct, lung and brain cortex.
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.