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Home / Primary Antibodies

Fadd Antibody (RQ6175)

SKU : BHA17110812

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NSJ Bioreagents

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Mfr.No.	RQ6175
Clonality	Polyclonal
Description	FADD, Fas-Associated protein with Death Domain, is a universal adaptor protein in apoptosis that mediates signaling of all known death domain-containing members of the TNF receptor superfamily. The FADD gene contains 2 exons and spans approximately 3.6 kb. By analysis of somatic cell hybrid panels and by fluorescence in situ hybridization, the FADD gene is mapped to 11q13.3. The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, thus, it participates in the death signaling initiated by these receptors.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	Amino acids EKENASVAGLVKALRACRLNLVADLVEEALMAQ from the rat protein were used as the immunogen for the Fadd antibody.
Isotype	IgG
Predicted Reactivity	Rat, Mouse
Reactivity	Rat, Mouse
Recombinant	No
Subcellular Location	Cytoplasmic, nuclear

Uniprot	Q8R2E7

Format	Antigen affinity purified
Purification	Affinity purified
Storage	After reconstitution, the Fadd antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	WB, IHC-P
Dilution	Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 2-5ug/ml

Product Manual	Data Sheet

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA17110812	RQ6175	100 ug	$419		Add to Cart

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