Estrogen receptor alpha is a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. (RefSeq)
Formulation
Antibody in PBS with 0.02% sodium azide and 50% glycerol
Host
Rabbit
Immunogen Region
A synthetic peptide specific to human ER alpha / ESR1 was used as the immunogen for the ER alpha antibody.
Isotype
IgG
Predicted Reactivity
Human
Reactivity
Human
Recombinant
No
Uniprot
P03372
Clone No
IE-5
Format
Purified
Purification
Affinity purified
Storage
Store the ER alpha antibody at -20°C.
Applications
IHC-P, WB
Dilution
Western blot: 1:500-1:2000,Immunohistochemistry (FFPE): 1:50-1:100