Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap. (UniProt)
Formulation
Antibody in PBS with 50% Glycerol and 0.03% ProClin 300
Host
Mouse
Immunogen Region
A human recombinant protein was used as the immunogen for this EIF4E antibody.