Rabbit Anti-Human EGFR (pTyr869) Polyclonal

Mfr.No.	SPC-1371, SPC-1371D, SPC-1371D-A390, SPC-1371D-A488, SPC-1371D-A594, SPC-1371D-BI, SPC-1371D-FITC
Immunogen Species	Human
Alternative Names	EGFR Antibody, NISBD2 Antibody, Errp Antibody, HER1 Antibody, Urogastrone Antibody, Epidermal growth factor receptor Antibody, Proto-oncogene c-ErbB-1 Antibody, mENA Antibody, Receptor tyrosine protein kinase ErbB 1 Antibody, Epidermal growth factor receptor (avian erythroblastic leukemia viral (v erb b) oncogene homolog) Antibody, Cell growth inhibiting protein 40 Antibody, PIG61 Antibody, Receptor tyrosine-protein kinase ErbB-1 Antibody, EGFR_HUMAN Antibody, EGF R Antibody, v-erb-b Avian erythroblastic leukemia viral oncogen homolog Antibody, erb-b2 receptor tyrosine kinase 1 Antibody, Epidermal growth factor receptor (erythroblastic leukemia viral (v erb b) oncogene homolog avian) Antibody, EGFR Antibody, Cell proliferation inducing protein 61 Antibody, Wa5 Antibody, SA7 Antibody, Species antigen 7 Antibody, Oncogen ERBB Antibody, wa2 Antibody, EC:2.7.10.1 Antibody, ERBB1 Antibody, Avian erythroblastic leukemia viral (v erb b) oncogene homolog Antibody, ERBB Antibody
Categories	Antibodies
Cellular Localization	Endosome Membrane, Endoplasmic Reticulum Membrane, Golgi Apparatus Membrane, Extracellular Space, Nuclear Membrane, Endosome, Single-Pass Type I Membrane Protein, Nucleus Membrane, Single-Pass Type I Membrane Protein Nucleus, Nucleus, Plasma Membrane, Cell Membrane, Secreted, Early Endosome Membrane, Multivesicular Body Internal Vesicle Lumen, Golgi Apparatus, Golgi Membrane, Apical Plasma Membrane, Basolateral Plasma Membrane, Shc-Egfr Complex, Cell Surface, Clathrin-Coated Vesicle Membrane, Cytoplasm, Endocytic Vesicle, Focal Adhesion, Integral Component Of Membrane, Membrane, Membrane Raft, Receptor Complex, Synapse, Perinuclear Region Of Cytoplasm, Protein Complex
Clonality	Polyclonal
Description	Rabbit Anti-Human EGFR (pTyr869) Polyclonal
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Host	Rabbit
Gross Weight (kg)	1.4
Immunogen	Synthetic phospho-peptide from human EGFR around the phosphorylation site of tyrosine 869 (pTyr869)., Homo Sapiens (Human)
Immunogen Region	Synthetic phospho-peptide from human EGFR around the phosphorylation site of tyrosine 869 (pTyr869).
Isotype	IgG
Launch Date	2018/03/07
Net Weight (g)	0.1
Reactivity	Rat, Mouse, Human
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)
Species Reactivity Medium	Mouse, Rat, Human
Tissue Specificity	Ubiquitously expressed. Isoform 2 is also expressed in ovarian cancers.

Swissprot	P00533
Accession Number	NP_005219.2
Gene Id	1956
Target	EGFR (pTyr869)
Research Area	Cell Signaling, Growth Factors, EGF, Protein Phosphorylation, Tyrosine Kinases, Receptor Tyrosine Kinases, Cancer, Tumor Biomarkers, Tumor Biomarker Receptors, Oncoproteins, Growth Factor Receptors

Buffer	PBS, pH 7.4, 150mM NaCl, 50% glycerol, 0.02% sodium azide
Dilutions	WB (1:250-1:1000); optimal dilutions for assays should be determined by the user.
Purification	Peptide Affinity Purified
Purity	Ubiquitously expressed. Isoform 2 is also expressed in ovarian cancers.
Scientific Background	EGFR is a receptor tyrosine kinase. Receptor for epidermal growth factor (EGF) and related growth factors including TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation.
Shipping Temperature	Blue Ice or 4°C
Specificity	Detects endogenous levels of EGFR only when phosphorylated at tyrosine 869 (pTyr869). Detects a band at ~175 kDa.
Storage	-20ºC
Storage Buffer	PBS, pH 7.4, 150mM NaCl, 50% glycerol, 0.02% sodium azide *Storage buffer may change when conjugated
Storage Temperature	-20°C

Applications	WB
Description	WB
Dilution	WB (1:250-1:1000); optimal dilutions for assays should be determined by the user.

Product Manual	SDS
SDS

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Combination SKU	Supplier No.	Conjugate	Size	Your price
BHA11918864-1	SPC-1371D	Unconjugated	100 ul	$331	Add to Cart
BHA11918864-2	SPC-1371D-A390	ATTO 390	100 ul	$385	Add to Cart
BHA11918864-3	SPC-1371D-A488	ATTO 488	100 ul	$384	Add to Cart
BHA11918864-4	SPC-1371D-A594	ATTO 594	100 ul	$384	Add to Cart
BHA11918864-5	SPC-1371D-BI	Biotin	100 ul	$380	Add to Cart
BHA11918864-6	SPC-1371D-FITC	FITC	100 ul	$375	Add to Cart

EGFR Antibody (pTyr869) - SPC-1371

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