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Home / Primary Antibodies / Polyclonal Antibodies

EGFR antibody

SKU : BHA10802661

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Mfr.No.	FNab02667
Alternative Names	EGFR ; ERBB ; ERBB1 ; HER1 ; mENA ; PIG61 ; ProtooncogenecErbB1
Background	The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.
Categories	Primary Antibodies
Clonality	polyclonal
Description	ERBB1, also mamed as EGFR, is a receptor for EGF, but also for other members of the EGF family, as TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. ERBB1 is involved in the control of cell growth and differentiation. Phosphorylates MUC1 in breast cancer cells and increases the interaction of MUC1 with C-SRC and CTNNB1/beta-catenin. Isoform 2/truncated isoform of ERBB1 may act as an antagonist. EGFR is associated with lung cancer. The antibody can recognize all the isoforms.
Host	Rabbit
Immunogen	epidermal growth factor receptor
Isotype	IgG
Molecular Weight	160 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	EGFR, ERBB, ERBB1, HER1, mENA, PIG61, Proto oncogene c ErbB 1

Uniprot	P00533
Gene Id	1956
Research Area	Signal Transduction, Metabolism, Cardiovascular, Cancer, Immunology
Weight	140kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC, FC

Description

ELISA ; WB ; IHC ; FC

Dilution

WB	1:1000-1:10000
IHC	1:50-1:500

Tested Application

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab02667.pdf

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA10802661	FNab02667	100ug	$280		Add to Cart

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