This gene encodes a protein that is a member of the M49 family of metallopeptidases. This cytoplasmic protein binds a single zinc ion with its zinc-binding motif (HELLGH) and has post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. Increased activity of this protein is associated with endometrial and ovarian cancers. Alternatively spliced transcript variants have been found for this gene.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Cleaves and degrades of the opioid peptide enkephalin. Also cleaves Arg-Arg-beta-naphthylamide.
Host
Rabbit
Immunogen
dipeptidyl-peptidase 3
Isotype
IgG
Molecular Weight
83 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Uniprot
Q9NY33
Gene Id
10072
Research Area
Cardiovascular, Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)