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Home / Antibodies

DNASE1L3 Antibody

SKU : BHA10552257

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA115883
Alternative Names	deoxyribonuclease I-like 3
Antigen	DNASE1L3
Categories	Primary Antibodies
Conjugate	Non-conjugated
Description	This gene encodes a member of the deoxyribonuclease I family. The encoded protein hydrolyzes DNA, is not inhibited by actin, and mediates the breakdown of DNA during apoptosis. Mutations in this gene are a cause of systemic lupus erythematosus-16. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Host	Rabbit
Immunogen	Fusion protein of Human DNASE1L3
Involvement In Disease	Systemic lupus erythematosus 16 (SLEB16)
Isotype	IgG
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	This gene encodes a member of the deoxyribonuclease I family. The encoded protein hydrolyzes DNA, is not inhibited by actin, and mediates the breakdown of DNA during apoptosis. Mutations in this gene are a cause of systemic lupus erythematosus-16. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Species	Homo Sapiens (Human)
Subcellular Location	Nucleus, Endoplasmic reticulum, Secreted

Uniprot	Q13609
Database Links	HGNC:2959 OMIM:602244 KEGG:hsa:1776 STRING:9606.ENSP00000316193 UniGene:Hs.476453
Function	Has DNA hydrolytic activity. Is capable of both single- and double-stranded DNA cleavage, producing DNA fragments with 3'-OH ends (By similarity). Can cleave chromatin to nucleosomal units and cleaves nucleosomal and liposome-coated DNA
Protein Families	DNase I family
Tissue Specificity	Liver and spleen.

Buffer	-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form	Liquid
Format	Liquid
Purification	Antigen affinity purification
Purity	Antigen affinity purification
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Storage Buffer	-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

ELISA	1:2000-1:5000
WB	1:500-1:2000

Tested Application

ELISA,WB;ELISA:1:2000-1:5000,WB:1:500-1:2000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10552257	CSB-PA115883	100μl	$279.30		Add to Cart
BHA10552257	CSB-PA115883	50μl	$168		Add to Cart

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