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Home / Primary Antibodies / Monoclonal Antibodies

DENND4C Antibody - SMC-610

SKU : BHA11933391

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StressMarq Biosciences Inc.

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Mfr.No.	SMC-610, SMC-610D, SMC-610D-A390, SMC-610D-A488, SMC-610D-A594, SMC-610D-ALP, SMC-610D-APC, SMC-610D-BI, SMC-610D-FITC, SMC-610D-HRP, SMC-610D-PCP, SMC-610D-RPE, SMC-610S
Immunogen Species	Human
Alternative Names	DENN domain-containing protein 4C antibody
Categories	Antibodies
Cellular Localization	Cell membrane, Cytoplasmic vesicle, Cytoplasm, Membrane
Certificate Of Analysis	A 1:1000 dilution of SMC-610 was sufficient for detection of DENND4C in A549, MEF cells by Western Blot analysis.
Clonality	Monoclonal
Description	Mouse Anti-Human DENND4C Monoclonal IgG1
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Host	Mouse
Gross Weight (kg)	1.4
Immunogen Region	Full Length Human Recombinant Dennd4c protein
Isotype	IgG1
Launch Date	2020/08/12
Net Weight (g)	0.1
Reactivity	Human, Mouse, Rat
Species Reactivity Medium	Mouse, Rat, Human
Tissue Specificity	Widely expressed

Swissprot	Q5VZ89
Accession Number	NM_017925
Gene Id	55667
Clone No	3E8
Research Area	Membrane Trafficking Proteins, Alzheimer's Disease, Cell Signaling, Golgi Proteins, Neurodegeneration, Parkinson's Disease, Growth Factors, Neuroscience, Protein Trafficking

Buffer	PBS pH 7.4, 50% glycerol, 0.09% Sodium Azide
Concentration	1mg/ml
Purification	Protein G Purified
Scientific Background	Dennd4c is a guanine nucleotide exchange factor (GEF) for Rab10, and required for GLUT4 translocation (1). It is associated with Alkuraya-Kucinskas Syndrome and Koolen-De Vries Syndrome (2) and interacts with the retromer (3).
Shipping Temperature	Blue Ice or 4°C
Specificity	Detects ~213 kDa.
Storage	-20ÂºC
Storage Buffer	PBS pH 7.4, 50% glycerol, 0.09% Sodium azide *Storage buffer may change when conjugated
Storage Temperature	-20°C

Applications	WB, ICC/IF, IP
Dilution	WB (1:1000); optimal dilutions for assays should be determined by the user.

Product Manual	SDS

Reference	1. Sano, H. et al. (2011). J Biol Chem. 286(19):16541-5. 2. https://www.genecards.org/cgi-bin/carddisp.pl gene=DENND4C 3. McMillan, K. et al. (2016). J Cell Biol. 214(4):4389400

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Combination SKU	Supplier No.	Conjugate	Size	Your price	Quantity
BHA11933391-1	SMC-610D	Unconjugated	100 ug	$387		Add to Cart
BHA11933391-2	SMC-610D-A390	ATTO 390	100 ug	$441		Add to Cart
BHA11933391-3	SMC-610D-A488	ATTO 488	100 ug	$440		Add to Cart
BHA11933391-4	SMC-610D-A594	ATTO 594	100 ug	$440		Add to Cart
BHA11933391-5	SMC-610D-ALP	Alkaline Phosphatase	100 ug	$433		Add to Cart
BHA11933391-6	SMC-610D-APC	APC	100 ug	$439		Add to Cart
BHA11933391-7	SMC-610D-BI	Biotin	100 ug	$436		Add to Cart
BHA11933391-8	SMC-610D-FITC	FITC	100 ug	$431		Add to Cart
BHA11933391-9	SMC-610D-HRP	HRP	100 ug	$427		Add to Cart
BHA11933391-10	SMC-610D-PCP	PerCP	100 ug	$439		Add to Cart
BHA11933391-11	SMC-610D-RPE	RPE	100 ug	$437		Add to Cart
BHA11933391-12	SMC-610S	Unconjugated	12 ug	$44		Add to Cart

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