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Home / Antibodies

CYLD Antibody (N1164)

SKU : BHA17103569

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NSJ Bioreagents

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Mfr.No.	N1164, N1164-25UG, N1164-100UG
Clonality	Polyclonal
Description	CYLD is involved in multiple physiological processes including immune response, osteoclastogenesis and spermatogenesis. It is a tumor suppressor via its negative regulation of NF-kB activation. CYLD is a deubiquitinase, removing ubiquitin chains from tumor-necrosis factor receptor-associated factor 2 (TRAF2) and thereby preventing its activation of IkB, a regulator of NF-kB. NF-kB remains sequestered in the cytoplasm, unable to translocate to the nucleus and initiate cell survival and oncogenetic signaling.
Formulation	0.5 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Host	Rabbit
Immunogen Region	A recombinant protein fragment from the N-termiinal region of human CYLD was used as the immunogen for this antibody.
Isotype	IgG
Predicted Reactivity	Human, Mouse
Reactivity	Human, Mouse
Recombinant	No

Gene Id	1540

Buffer	1X PBS, pH 7.4
Concentration	0.5 mg/ml
Format	Purified
Purification	Protein A affinity chromatography
Storage	Aliquot the CYLD antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Applications	WB
Dilution	Western blot: 2-5ug/ml

Product Manual	Data Sheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17103569-1	N1164-25UG	25ug	$209		Add to Cart
BHA17103569-2	N1164-100UG	100ug	$419		Add to Cart

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