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Home / Antibodies

Cyclin D1 Antibody / CCND1 (V8652SAF)

SKU : BHA17127664

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NSJ Bioreagents

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Mfr.No.	V8652SAF-100UG
Clonality	Recombinant Mouse Monoclonal
Description	Recognizes a protein of 36kDa, identified as cyclin D1. Cyclin D1, one of the key cell cycle regulators, is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. This antibody neutralizes the activity of cyclin D1 in vivo. About 60% of mantle cell lymphomas (MCL) contain a t(11; 14)(q13; q32) translocation resulting in over-expression of cyclin D1. This antibody is useful in identifying mantle cell lymphomas (cyclin D1 positive) from CLL/SLL and follicular lymphomas (cyclin D1 negative). Occasionally, hairy cell leukemia and plasma cell myeloma weakly express Cyclin D1.
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Mouse
Immunogen Region	A portion of amino acids 200-295 from the human protein was used as the immunogen for the recombinant Cyclin D1 antibody.
Isotype	Mouse IgG2a, kappa
Species Reactivity	Human
Note	Optimal dilution of the recombinant Cyclin D1 antibody should be determined by the researcher.

Uniprot	P24385

Format	Purified
Purity	Protein G affinity chromatography
Storage	Store the recombinant Cyclin D1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	IHC-P
Description	Immunohistochemistry (FFPE): 1-2ug/ml for 30 minutes at RT

Product Manual	<a href="https://www.nsjbio.com/tds-pdf/recombinant-cyclin-d1-antibody-rccnd1-4752-v8652" target="_blank">Datasheet</a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA17127664	V8652SAF-100UG	100 ug	$499		Add to Cart

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