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Home / Primary Antibodies

Cyclin D1 Antibody / CCND1 (V8053SAF)

SKU : BHA17127179

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NSJ Bioreagents

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Mfr.No.	V8053SAF-100UG
Clonality	Monoclonal (mouse origin)
Description	Recognizes a protein of 36kDa, identified as cyclin D1. Cyclin D1, one of the key cell cycle regulators, is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. This antibody neutralizes the activity of cyclin D1 in vivo. About 60% of mantle cell lymphomas (MCL) contain a t(11; 14)(q13; q32) translocation resulting in over-expression of cyclin D1. This antibody is useful in identifying mantle cell lymphomas (cyclin D1 positive) from CLL/SLL and follicular lymphomas (cyclin D1 negative). Occasionally, hairy cell leukemia and plasma cell myeloma weakly express Cyclin D1.
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Mouse
Immunogen Region	A recombinant human partial protein (amino acids 115-270) was used as the immunogen for this Cyclin D1 antibody.
Isotype	Mouse IgG2b, kappa
Species Reactivity	Human
Note	Optimal dilution of the antibody should be determined by the researcher.

Uniprot	P24385

Format	Purified
Purity	Protein G affinity chromatography
Storage	Store the Cyclin D1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	ELISA
Description	ELISA (order BSA-free format for coating)

Product Manual	<a href="https://www.nsjbio.com/tds-pdf/cyclin-d1-antibody-ccnd1-3548-v8053" target="_blank">Datasheet</a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA17127179	V8053SAF-100UG	100 ug	$499		Add to Cart

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