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Home / Antibodies

Cyclin A1 Antibody / CCNA1 (V8293)

SKU : BHA17119328

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NSJ Bioreagents

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Mfr.No.	V8293, V8293-20UG, V8293-100UG
Clonality	Monoclonal (mouse origin)
Description	The critical role that the family of regulatory proteins known as cyclins play in eukaryotic cell cycle regulation is well established. The best-characterized cyclin complex is the mitotic cyclin B/Cdc2 p34 kinase, the active component of maturing promoting factor. Cyclin A accumulates prior to cyclin B in the cell cycle, appears to be involved in control of S phase and has been shown to associate with cyclin-dependent kinase-2 (Cdk2). In addition, cyclin A has been implicated in cell transformation and is found in complexes with E1A, transcription factors DRTF1 and E2F, and retinoblastoma protein p110. A second form of cyclin A, named cyclin A1 because of its high sequence homology to Xenopus cyclin A1, is most highly expressed in germ cells. It has been proposed that cyclin A1 can associate with Cdk2, p39 and Cdc2 p34. The antibody detects Xenopus cyclin A in blots. Cyclin A1 is the embryonic cyclin which is present in Xenopus eggs.
Formulation	0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Host	Mouse
Immunogen Region	Recombinant full-length Xenopus laevis Cyclin A1 protein was used as the immunogen for the Cyclin A1 antibody.
Isotype	Mouse IgG1, kappa
Species Reactivity	Xenopus laevis, Human
Note	Optimal dilution of the Cyclin A1 antibody should be determined by the researcher.

Format	Purified
Purity	Protein G affinity chromatography
Storage	Store the Cyclin A1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	WB
Description	Western blot: 1-2ug/ml

Product Manual	Datasheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17119328-1	V8293-20UG	20ug	$219		Add to Cart
BHA17119328-2	V8293-100UG	100ug	$499		Add to Cart

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