cAMP responsive element binding protein 1, is a protein that in humans is encoded by the CREB1 gene. This protein binds the cAMP response element, a DNA nucleotide sequence present in many viral and cellular promoters. The binding of CREB1 stimulates transcription. This transcription factor is a member of the leucine zipper family of DNA-binding proteins. It binds as a homodimer to the cAMP-responsive element, an octameric palindrome. CREB is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway.
Formulation
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host
Rabbit
Immunogen Region
Human partial recombinant protein (AA 1-177) was used as the immunogen for this CREB antibody.
Isotype
IgG
Predicted Reactivity
Human, Rat
Reactivity
Human, Rat
Recombinant
No
Gene Id
12912
Format
Antigen affinity purified
Purification
Antigen affinity
Storage
After reconstitution, the CREB antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.